Abstract：
Benzophenone-3 (BP-3) has been widely used as a typical ultraviolet (UV) filter in various personal care products. While BP-3 and its derivatives (BPs) have been detected in various environmental matrices, very little is known about the concentration profile of BPs in human hair. The associations of BPs in human hair with those in indoor dust samples collected from the same locations remain largely unclear. In this study, a total of 258 indoor dust samples and 66 human hair samples were collected across China and analyzed to determine the presence of BP-3 and its derivatives. The BP-3 concentrations ranged from 0.386 to 1230 ng/g dw in indoor dust and from 0.149 to 696 ng/g dw in human hair. No difference was found between BPs in indoor dust samples from different geographic regions (p > 0.05), whereas relatively higher BP concentrations were observed for dust from urban regions than dust from rural ones (p < 0.05). A positive correlation was found between the BP-3 concentrations of indoor dust and human hair samples (p < 0.05). The estimated daily intake (EDI) of BPs for humans from indoor dust showed a gender difference (females > males; p < 0.05), with the highest EDI value being found in Southwest China (males: 35.5 pg/kg bw/day; females: 40.6 pg/kg bw/day). This study provides the concentration profiles of BPs in human hair and elucidates the associations between the BP concentrations in indoor dust samples and human hair samples collected across China.
摘要：
二苯甲酮-3（BP-3）已广泛用作各种个人护理产品中的典型紫外线（UV）过滤剂。虽然已经在各种环境基质中检测到BP-3及其衍生物(BPs),关于人发中BP的浓度分布知之甚少。人发中的BP与从同一地点收集的室内灰尘样品中的BP之间的关联仍不清楚。在这项研究中,在中国收集了258个室内灰尘样本和66个人发样本，并进行了分析以确定BP-3及其衍生物的存在。室内灰尘中的BP-3浓度范围为0.386至1230ng/gdw，人发中的BP-3浓度范围为0.149至696ng/gdw。来自不同地理区域的室内灰尘样品中的BP之间没有发现差异（p>0.05），而与农村地区相比，城市地区的粉尘观察到的BP浓度相对较高（p<0.05）。室内粉尘的BP-3浓度与人发样呈正相关(p<0.05)。室内灰尘对人体BPs的估计每日摄入量（EDI）显示出性别差异（女性>男性；p<0.05），中国西南地区的EDI值最高（男性：35.5pg/kgbw/天；女性：40.6pg/kgbw/天）。这项研究提供了人发中BP的浓度分布，并阐明了室内灰尘样品中BP浓度与中国各地收集的人发中BP浓度之间的关联。
