Abstract：
The Appraisal of Guidelines Research and Evaluation (AGREE) II instrument was developed to evaluate the quality of clinical practice guidelines. Evidence suggests that development, reporting, and appraisal of guidelines on surgical interventions may be better informed by modification of the instrument.
We aimed to develop an AGREE II extension specifically designed for appraisal of guidelines of surgical interventions.
In a three-part project funded by the United European Gastroenterology and the European Association for Endoscopic Surgery, (i) we identified factors that were associated with higher quality of surgical guidelines, (ii) we statistically calibrated the AGREE II instrument in the context of surgical guidelines using correlation, reliability, and factor analysis, and (iii) we undertook a Delphi consensus process of stakeholders to inform the development of an AGREE II extension instrument for surgical interventions.
Several features were prioritized by stakeholders as of particular importance for guidelines of surgical interventions, including development of a guideline protocol, consideration of practice variability and surgical expertise in different settings, and specification of infrastructures required to implement the recommendations. The AGREE-S-AGREE II extension instrument for surgical interventions has 25 items, compared to the 23 items of the original AGREE II instrument, organized into the following 6 domains: Scope and purpose, Stakeholders, Evidence synthesis, Development of recommendations, Editorial independence, and Implementation and update. As the original instrument, it concludes with an overall appraisal of the quality of the guideline and a judgement on whether the guideline is recommended for use. Several items were amended and rearranged among domains, and an item was deleted. The Rigor of Development domain of the original AGREE II was divided into Evidence Synthesis and Development of Recommendations. Items of the AGREE II domain Clarity of Presentation were incorporated in the new domain Development of Recommendations. Three new items were introduced, addressing the development of a guideline protocol, support by a guideline methodologist, and consideration of surgical experience/expertise.
The AGREE-S appraisal instrument has been developed to be used for assessment of the methodological and reporting quality of guidelines on surgical interventions.
We aimed to develop an AGREE II extension specifically designed for appraisal of guidelines of surgical interventions.
In a three-part project funded by the United European Gastroenterology and the European Association for Endoscopic Surgery, (i) we identified factors that were associated with higher quality of surgical guidelines, (ii) we statistically calibrated the AGREE II instrument in the context of surgical guidelines using correlation, reliability, and factor analysis, and (iii) we undertook a Delphi consensus process of stakeholders to inform the development of an AGREE II extension instrument for surgical interventions.
Several features were prioritized by stakeholders as of particular importance for guidelines of surgical interventions, including development of a guideline protocol, consideration of practice variability and surgical expertise in different settings, and specification of infrastructures required to implement the recommendations. The AGREE-S-AGREE II extension instrument for surgical interventions has 25 items, compared to the 23 items of the original AGREE II instrument, organized into the following 6 domains: Scope and purpose, Stakeholders, Evidence synthesis, Development of recommendations, Editorial independence, and Implementation and update. As the original instrument, it concludes with an overall appraisal of the quality of the guideline and a judgement on whether the guideline is recommended for use. Several items were amended and rearranged among domains, and an item was deleted. The Rigor of Development domain of the original AGREE II was divided into Evidence Synthesis and Development of Recommendations. Items of the AGREE II domain Clarity of Presentation were incorporated in the new domain Development of Recommendations. Three new items were introduced, addressing the development of a guideline protocol, support by a guideline methodologist, and consideration of surgical experience/expertise.
The AGREE-S appraisal instrument has been developed to be used for assessment of the methodological and reporting quality of guidelines on surgical interventions.
摘要：
开发了评估指南研究与评估（AGREE）II工具来评估临床实践指南的质量。证据表明，发展，reporting,通过修改仪器，可以更好地了解手术干预指南的评估。
我们的目标是开发一个AGREEII扩展，专门用于评估手术干预指南。
在由欧洲胃肠病学和欧洲内镜手术协会资助的三部分项目中，（i）我们确定了与更高质量的手术指南相关的因素，(Ii)我们在手术指南的背景下使用相关性对AGREEII仪器进行了统计校准，可靠性,和因子分析，（iii）我们进行了利益相关者的Delphi共识过程，以告知用于手术干预的AGREEII扩展工具的开发。
利益相关者优先考虑了一些特征，这些特征对外科手术干预指南特别重要。包括制定指导方针，考虑不同环境下的实践差异和外科专业知识，以及实施建议所需的基础设施规范。用于外科手术的AGREE-S-AGREEII扩展仪器有25个项目，与原始AGREEII文书的23项相比，分为以下6个领域：范围和目的，利益相关者，证据综合，发展建议，编辑独立,以及实施和更新。作为原始乐器，它最后对指南的质量进行了总体评估，并对是否建议使用该指南进行了判断。几个项目在域之间进行了修改和重新排列，并删除了一个项目。原始AGREEII的发展领域的严格性分为证据综合和建议的发展。AGREEII领域的项目介绍的清晰度已纳入新领域的建议开发中。引入了三个新项目，解决指导协议的制定，由指导方法学家支持，并考虑手术经验/专业知识。
AGREE-S评估工具已被开发用于评估外科干预指南的方法学和报告质量。
我们的目标是开发一个AGREEII扩展，专门用于评估手术干预指南。
在由欧洲胃肠病学和欧洲内镜手术协会资助的三部分项目中，（i）我们确定了与更高质量的手术指南相关的因素，(Ii)我们在手术指南的背景下使用相关性对AGREEII仪器进行了统计校准，可靠性,和因子分析，（iii）我们进行了利益相关者的Delphi共识过程，以告知用于手术干预的AGREEII扩展工具的开发。
利益相关者优先考虑了一些特征，这些特征对外科手术干预指南特别重要。包括制定指导方针，考虑不同环境下的实践差异和外科专业知识，以及实施建议所需的基础设施规范。用于外科手术的AGREE-S-AGREEII扩展仪器有25个项目，与原始AGREEII文书的23项相比，分为以下6个领域：范围和目的，利益相关者，证据综合，发展建议，编辑独立,以及实施和更新。作为原始乐器，它最后对指南的质量进行了总体评估，并对是否建议使用该指南进行了判断。几个项目在域之间进行了修改和重新排列，并删除了一个项目。原始AGREEII的发展领域的严格性分为证据综合和建议的发展。AGREEII领域的项目介绍的清晰度已纳入新领域的建议开发中。引入了三个新项目，解决指导协议的制定，由指导方法学家支持，并考虑手术经验/专业知识。
AGREE-S评估工具已被开发用于评估外科干预指南的方法学和报告质量。
