UNASSIGNED: An interdisciplinary team of experts from the GC-HBOC has evaluated the available data on risk modification in the presence of pathogenic mutations in these genes based on a structured literature search and through a formal consensus process.
UNASSIGNED: The goal of this work is to better assess individual disease risk and, on this basis, to derive clinical recommendations for patient counseling and care at the centers of the GC-HBOC from the initial consultation prior to genetic testing to the use of individual risk-adapted preventive/therapeutic measures.
UNASSIGNED:来自GC-HBOC的跨学科专家团队基于结构化的文献检索并通过正式的共识过程,评估了在这些基因中存在致病性突变的情况下风险改变的可用数据。
UNASSIGNED:这项工作的目标是更好地评估个体疾病风险,在此基础上,从基因检测前的初次咨询到使用个体风险适应的预防/治疗措施,得出GC-HBOC中心患者咨询和护理的临床建议。