关键词: BT angle BV angle fetal MRI posterior fossa fluid collections prenatal ultrasound

来  源:   DOI:10.3389/fmed.2022.878906   PDF(Pubmed)

Abstract:
UNASSIGNED: To assess the reproducibility of brainstem-vermis (BV) and brainstem-tentorium (BT) angles measured by fetal Magnetic Resonance Imaging (MRI) during second half of pregnancy in normal and abnormal fetuses. Secondly, to assess reproducibility of two alternative methodologies to measure the brainstem-tentorium angle (BT1 and BT2) proposed by our group that could be more reliable in fetuses with posterior fossa fluid collection (PFFC) anomalies. Finally, to describe the evolution of BV and BT angles along gestation in normal fetuses.
UNASSIGNED: We conducted a cross-sectional study of BV and BT angles obtained by MRI performed at our center, in 22 fetuses with PFFC and 8 fetuses without PFFC to calculate both angles\' reproducibility and the correlation between them and the gestational age.
UNASSIGNED: We found good interobserver reproducibility for the BV, BT1 and BT2 angles (Intraclass correlation coefficient: 0.98; 0.89 and 0.88 for each of these angles, with p < 0.001). In patients with PFFC the BT angle could not always be measured. BT angle presented a positive relationship with gestational age (p = 0.002) but BV angle stayed stable. The measurements of BV, BT1, and BT2 angles can be reliably performed by MRI with good interobserver reproducibility.
UNASSIGNED: BV angle stays stable during pregnancy, whereas BT angle tends to augment with gestational age.
摘要:
评估正常和异常胎儿在妊娠后半期通过胎儿磁共振成像(MRI)测量的脑干and(BV)和脑干-小脑(BT)角度的可重复性。其次,评估我们小组提出的两种测量脑干-幕部角度(BT1和BT2)的替代方法的可重复性,这些方法在有后颅窝积液(PFFC)异常的胎儿中可能更可靠。最后,描述正常胎儿BV和BT角度沿妊娠的演变。
我们对在我们中心进行的MRI获得的BV和BT角度进行了横断面研究,在22例使用PFFC的胎儿和8例未使用PFFC的胎儿中,计算两个角度的可重复性以及它们与胎龄之间的相关性。
我们发现BV的观察者间重现性好,BT1和BT2角度(类相关系数:0.98;每个角度为0.89和0.88,p<0.001)。在PFFC患者中,无法始终测量BT角度。BT角与胎龄呈正相关(p=0.002),但BV角保持稳定。BV的测量,BT1和BT2角度可以通过MRI以良好的观察者间再现性可靠地执行。
BV角度在怀孕期间保持稳定,而BT角倾向于随着胎龄增加。
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