UNASSIGNED: Search the Web of Science, the Cochrane Library, PubMed, and Embase databases with acupuncture randomized controlled trials for the treatment of patients with PDS. Strictly according to inclusion and exclusion quality assessment standards, the qualified ones are used to study the optimum extraction and data by two independent reviewers. Stata 15.0 software was used for meta-analysis.
UNASSIGNED: We initially identified 63 studies, of which five (1253 participants) were eventually included in our analysis. There were 643 cases in the experimental group and 610 cases in the control group. Acupuncture had a significant effect on the total therapeutic effect (OTE) at week 4 (OR 4.74, 95% CI 02.88-7.83, Z = 6.10, P = 0 < 0.05). Significantly improved NDI (Nepean dyspepsia index) scores of PDS patients at week 4 (SMD 0.61, 95% CI 0.48 to 0.74). Significantly improved NDI scores in PDS patients at week 16 (SMD 0.49, 95% CI 0.27 to 0.71). After acupuncture treatment, the SID (dyspepsia symptom index) score of PDS patients decreased significantly at week 4 (SMD-0.52, 95% CI -0.73 to -0.32) and week 16 (SMD-0.59, 95% CI -0.81 to -0.36). Postprandial satiety scores (SMD-0.63, 95% CI -0.76 to -0.50) and early satiety scores (SMD-0.51, 95% CI -0.64 to -0.37) were also significantly lower at week 4 after acupuncture.
UNASSIGNED: This study highlighted that the acupuncture could significantly improve the overall therapeutic effect of PDS patients, alleviate the symptoms of postprandial fullness and early satiety, and improve the quality of life of patients. Our results supported that acupuncture was an effective therapeutic strategy for postprandial distress syndrome.
■搜索科学网,Cochrane图书馆,PubMed,和Embase数据库与针灸随机对照试验治疗PDS患者。严格按照纳入和排除质量评定标准,合格的被用来研究最佳提取和数据由两个独立的审查。采用Stata15.0软件进行Meta分析。
■我们最初确定了63项研究,其中5名(1253名参与者)最终被纳入我们的分析.实验组643例,对照组610例。针刺对第4周的总疗效(OTE)有显著影响(OR4.74,95%CI02.88~7.83,Z=6.10,P=0<0.05)。在第4周时,PDS患者的NDI(Nepean消化不良指数)评分显着改善(SMD0.61,95%CI0.48至0.74)。PDS患者在第16周时NDI评分显著改善(SMD0.49,95%CI0.27~0.71)。针灸治疗后,PDS患者的SID(消化不良症状指数)评分在第4周(SMD-0.52,95%CI-0.73~-0.32)和第16周(SMD-0.59,95%CI-0.81~-0.36)显著下降.针刺后第4周,餐后饱腹感评分(SMD-0.63,95%CI-0.76至-0.50)和早期饱腹感评分(SMD-0.51,95%CI-0.64至-0.37)也显着降低。
■这项研究强调,针灸可以显着提高PDS患者的整体治疗效果,缓解餐后饱腹感和早期饱腹感的症状,提高患者的生活质量。我们的结果支持针灸是餐后窘迫综合征的有效治疗策略。