Abstract：
OBJECTIVE: To compare clinical findings and urodynamic parameters according to trabeculation grade and analyze their correlations with trabeculation severity in neurogenic bladder caused by suprasacral spinal cord injury (SCI).
METHODS: A retrospective chart review was performed of neurogenic bladder caused by SCI. Bladder trabeculation grade was compared with SCI-related clinical parameters and bladder-related urodynamic parameters.
RESULTS: In SCI patients, factors such as disease duration, bladder capacity, detrusor pressure, peak detrusor pressure values, and compliance were significantly different between different grades of bladder trabeculation, while neurological level of injury, completeness, and detrusor sphincter dyssynergia had no clear relationship with bladder trabeculation grade. In the correlation analysis, vesicoureteral reflux was moderately correlated with trabeculation grade (correlation coefficient 0.433), while the correlation coefficients of disease duration, involuntary detrusor contraction, and bladder filling volume were between 0.3 and 0.4.
CONCLUSIONS: Bladder trabeculation with suprasacral-type neurogenic bladder was graded. Although disease duration was positively correlated with bladder trabeculation grade, differences in the neurological level of injury or American Spinal Injury Association Impairment Scale score were not observed. Bladder volume, peak detrusor pressure, compliance, reflex volume, and vesicoureteral reflux also showed significant differences according to trabeculation grade. Vesicoureteral reflux was moderately correlated with trabeculation grade.
METHODS: A retrospective chart review was performed of neurogenic bladder caused by SCI. Bladder trabeculation grade was compared with SCI-related clinical parameters and bladder-related urodynamic parameters.
RESULTS: In SCI patients, factors such as disease duration, bladder capacity, detrusor pressure, peak detrusor pressure values, and compliance were significantly different between different grades of bladder trabeculation, while neurological level of injury, completeness, and detrusor sphincter dyssynergia had no clear relationship with bladder trabeculation grade. In the correlation analysis, vesicoureteral reflux was moderately correlated with trabeculation grade (correlation coefficient 0.433), while the correlation coefficients of disease duration, involuntary detrusor contraction, and bladder filling volume were between 0.3 and 0.4.
CONCLUSIONS: Bladder trabeculation with suprasacral-type neurogenic bladder was graded. Although disease duration was positively correlated with bladder trabeculation grade, differences in the neurological level of injury or American Spinal Injury Association Impairment Scale score were not observed. Bladder volume, peak detrusor pressure, compliance, reflex volume, and vesicoureteral reflux also showed significant differences according to trabeculation grade. Vesicoureteral reflux was moderately correlated with trabeculation grade.
摘要：
目的：比较脊髓骶上损伤（SCI）引起的神经源性膀胱的临床表现和尿动力学参数，并分析其与小梁严重程度的相关性。
方法：对SCI引起的神经源性膀胱进行回顾性分析。将膀胱小梁分级与SCI相关的临床参数和膀胱相关的尿动力学参数进行比较。
结果：在SCI患者中，疾病持续时间等因素，膀胱容量,逼尿肌压力,逼尿肌压力峰值,不同级别的膀胱小梁之间的依从性有显著差异，虽然神经损伤水平，完整性，逼尿肌括约肌协同失调与膀胱小梁分级无明显关系。在相关性分析中，膀胱输尿管反流与小梁分级中度相关（相关系数0.433），而疾病持续时间的相关系数，逼尿肌非自愿收缩，膀胱充盈量在0.3～0.4之间。
结论：膀胱小梁形成伴骶上型神经源性膀胱分级。尽管病程与膀胱小梁分级呈正相关,未观察到神经系统损伤程度或美国脊髓损伤协会损伤量表评分的差异。膀胱容积,逼尿肌峰值压力,合规,反射体积,根据小梁分级，膀胱输尿管反流也显示出显着差异。膀胱输尿管反流与小梁分级中度相关。
方法：对SCI引起的神经源性膀胱进行回顾性分析。将膀胱小梁分级与SCI相关的临床参数和膀胱相关的尿动力学参数进行比较。
结果：在SCI患者中，疾病持续时间等因素，膀胱容量,逼尿肌压力,逼尿肌压力峰值,不同级别的膀胱小梁之间的依从性有显著差异，虽然神经损伤水平，完整性，逼尿肌括约肌协同失调与膀胱小梁分级无明显关系。在相关性分析中，膀胱输尿管反流与小梁分级中度相关（相关系数0.433），而疾病持续时间的相关系数，逼尿肌非自愿收缩，膀胱充盈量在0.3～0.4之间。
结论：膀胱小梁形成伴骶上型神经源性膀胱分级。尽管病程与膀胱小梁分级呈正相关,未观察到神经系统损伤程度或美国脊髓损伤协会损伤量表评分的差异。膀胱容积,逼尿肌峰值压力,合规,反射体积,根据小梁分级，膀胱输尿管反流也显示出显着差异。膀胱输尿管反流与小梁分级中度相关。
