Abstract：
In Poland, drotaverine is the most frequently purchased antispasmodic, yet there is a paucity of real-world data on its use. We evaluated the profiles of patients who used drotaverine, and we investigated prescription patterns among general practitioners (GPs). In this cross-sectional, questionnaire-based study, we asked patients who purchased drotaverine about their reasons for using it, its perceived efficacy, satisfaction with treatment, and physician consultation. We also asked GPs about the status of drotaverine in their practice. Among 650 recruited patients, 74% used drotaverine for pain, 67% for cramps, and 19% for abdominal discomfort. Approximately 83% of patients purchased drotaverine without a physician\'s advice. Patients who used it after a physician\'s advice were more frequently female, older, and less educated. For all symptoms, mean severity scores decreased by ~5 points (0-10 scale) after the first dose. Ninety-eight percent of patients were satisfied with drotaverine. Among 210 GPs, the percentages prescribing drotaverine were: 42% for irritable bowel syndrome, 89% for cholelithiasis, 60% as supportive therapy for urinary infections, 89% for nephrolithiasis, and 75% for menstruation pain. The GPs perceived drotaverine as more useful, effective, and tolerable than other drugs for abdominal pain or cramps. Drotaverine significantly reduced the severity of all symptoms for which it was taken, and it was perceived as effective and tolerable.
摘要：
在波兰,drotaverine是最常购买的抗痉挛药，然而，关于其使用的现实世界数据却很少。我们评估了使用drotaverine的患者的情况，我们调查了全科医生（GP）的处方模式。在这个横截面中，基于问卷的研究，我们询问购买drotaverine的患者使用它的原因，它的感知功效，满意的治疗，和医生咨询。我们还向全科医生询问了drotaverine在实践中的状况。在650名招募的患者中，74%的人使用drotaverine治疗疼痛,67%的抽筋，19％为腹部不适。大约83％的患者在没有医生建议的情况下购买了drotaverine。在医生的建议下使用它的患者更常见的是女性，年长的,受教育程度较低。对于所有症状，第一次给药后平均严重程度评分下降~5分(0-10分)。98%的患者对drotaverine感到满意。在210名全科医生中，处方drotaverine的百分比是：肠易激综合征的42%，89%为胆石症，60%作为泌尿系感染的支持治疗,89%为肾结石，75%为月经疼痛。全科医生认为drotaverine更有用，有效,并且比其他药物更能耐受腹痛或痉挛。Drotaverine显着降低了服用的所有症状的严重程度，它被认为是有效和可以容忍的。
