When LDL Cholesterol Is Not LDL Cholesterol: LpX, A Clinical Lesson.

当 LDL 胆固醇不是 LDL 胆固醇时 ： LpX ，临床课程.

• 发表时间: Jun 2022 1
• 来源期刊: JACC Case Rep
• DOI: 10.1016/j.jaccas.2022.03.009
• PMID: 35677796
• 文章类型: Case Reports
• 作者列表: Huygen LPM,Westerink J,Mol GC,Bemelmans RHH

关键词: ApoB, apolipoprotein B; HDL, high-density lipoprotein; HDL-C, high-density lipoprotein cholesterol; LDL, low-density lipoprotein; LDL-C, low-density lipoprotein cholesterol; LpX, lipoprotein X; TC, total cholesterol; VLDL, very-low-density lipoprotein; apolipoprotein B; cholestasis; hypercholesterolemia; lipoprotein X

Abstract

LpX is a lipoprotein formed in cholestatic conditions and often erroneously reported as LDL-C. A low ApoB level can support the diagnosis of LpX. Treatment should not automatically focus on lowering serum lipid levels, but primarily on resolving the cause of cholestasis. (Level of Difficulty: Advanced.).

摘要

LpX是在胆汁淤积条件下形成的脂蛋白，经常被错误地报告为LDL-C。低ApoB水平可以支持LpX的诊断。治疗不应自动集中于降低血脂水平，但主要是解决胆汁淤积的原因。（难度等级：高级。).