PDF(Pubmed)
Abstract：
UNASSIGNED: Diagnosis of pancreatic lesions remains a clinical challenge. Early and accurate diagnosis is extremely important for improving the therapeutic usefulness of pancreatic cancers and Endoscopic ultrasonography - fine needle aspiration (EUS-FNA) cytology has come up with this advantage. For current study the authors evaluated the diagnostic accuracy of EUS-FNAC by applying PSC system for reporting pancreaticobiliary cytology and Calculated the malignancy risk associated with the diagnostic categories.
UNASSIGNED: A retrospective study over the period of 2.5 years (April 2017 to Oct 2019) 60 patients in our cohort EUS-FNAC guided unstained fixed and unfixed slides received of pancreatic lesion and were stained with Papanicolau and Giemsa using standard technique and immunocytochemistry, where required Application of Papanicolaou Society of Cytopathology system for reporting pancreaticobiliary cytology Histopathological and clinical follow-up were retrieved.
UNASSIGNED: Our study has comparable results with sensitivity, specificity, PPV, and NPV of 92.8%, 100%, 100%, and 92.59%, respectively. Fuurthermore, a diagnostic accuracy of 96.2%. Risk of malignancy is lower for benign and indeterminate category whereas it is higher for suspicious and malignant categories.
UNASSIGNED: The application of the new proposed terminology for pancreaticobiliary cytology brings standardization. Final diagnosis can be reached by the multidisciplinary approach of EUS-FNA cytology, cell block preparation, immunocytochemistry, and immunohistochemistry; if required, can be adopted as an alternative approach to biopsy. The present study showed high sensitivity and specificity for EUS-FNA in the diagnosis of pancreatic carcinoma, which may influence the treatment plans of both surgeons and oncologists.
UNASSIGNED: A retrospective study over the period of 2.5 years (April 2017 to Oct 2019) 60 patients in our cohort EUS-FNAC guided unstained fixed and unfixed slides received of pancreatic lesion and were stained with Papanicolau and Giemsa using standard technique and immunocytochemistry, where required Application of Papanicolaou Society of Cytopathology system for reporting pancreaticobiliary cytology Histopathological and clinical follow-up were retrieved.
UNASSIGNED: Our study has comparable results with sensitivity, specificity, PPV, and NPV of 92.8%, 100%, 100%, and 92.59%, respectively. Fuurthermore, a diagnostic accuracy of 96.2%. Risk of malignancy is lower for benign and indeterminate category whereas it is higher for suspicious and malignant categories.
UNASSIGNED: The application of the new proposed terminology for pancreaticobiliary cytology brings standardization. Final diagnosis can be reached by the multidisciplinary approach of EUS-FNA cytology, cell block preparation, immunocytochemistry, and immunohistochemistry; if required, can be adopted as an alternative approach to biopsy. The present study showed high sensitivity and specificity for EUS-FNA in the diagnosis of pancreatic carcinoma, which may influence the treatment plans of both surgeons and oncologists.
摘要：
■胰腺病变的诊断仍然是一个临床挑战。早期和准确的诊断对于提高胰腺癌的治疗有效性极为重要，超声内镜-细针穿刺（EUS-FNA）细胞学检查具有这一优势。对于当前的研究，作者通过应用PSC系统报告胰胆管细胞学来评估EUS-FNAC的诊断准确性，并计算与诊断类别相关的恶性肿瘤风险。
■一项为期2.5年（2017年4月至2019年10月）的回顾性研究，在我们的队列EUS-FNAC中，有60例患者接受了胰腺病变的未染色固定和未固定载玻片，并使用标准技术和免疫细胞化学进行了Papanicolau和Giemsa染色，如有必要，应用Papanicolaou细胞病理学学会系统报告胰胆管细胞学组织病理学和临床随访。
■我们的研究结果与灵敏度相当，特异性，PPV,净现值为92.8%，100%,100%,和92.59%，分别。Fuupurt,诊断准确率为96.2%。良性和不确定类别的恶性肿瘤风险较低，而可疑和恶性类别的恶性肿瘤风险较高。
■新提议的胰胆管细胞学术语的应用带来了标准化。最终诊断可以通过EUS-FNA细胞学的多学科方法来实现，细胞块制备，免疫细胞化学,和免疫组织化学；如果需要，可以作为活检的替代方法。本研究显示EUS-FNA在胰腺癌诊断中具有较高的敏感性和特异性。这可能会影响外科医生和肿瘤学家的治疗计划。
■一项为期2.5年（2017年4月至2019年10月）的回顾性研究，在我们的队列EUS-FNAC中，有60例患者接受了胰腺病变的未染色固定和未固定载玻片，并使用标准技术和免疫细胞化学进行了Papanicolau和Giemsa染色，如有必要，应用Papanicolaou细胞病理学学会系统报告胰胆管细胞学组织病理学和临床随访。
■我们的研究结果与灵敏度相当，特异性，PPV,净现值为92.8%，100%,100%,和92.59%，分别。Fuupurt,诊断准确率为96.2%。良性和不确定类别的恶性肿瘤风险较低，而可疑和恶性类别的恶性肿瘤风险较高。
■新提议的胰胆管细胞学术语的应用带来了标准化。最终诊断可以通过EUS-FNA细胞学的多学科方法来实现，细胞块制备，免疫细胞化学,和免疫组织化学；如果需要，可以作为活检的替代方法。本研究显示EUS-FNA在胰腺癌诊断中具有较高的敏感性和特异性。这可能会影响外科医生和肿瘤学家的治疗计划。
