关键词: anti-mullerian hormone hyperbaric oxygen ovarian cystectomy ovarian reserve function post oophorocystectomy

来  源:   DOI:10.3389/fsurg.2022.877114   PDF(Pubmed)

Abstract:
UNASSIGNED: This study aims to explore the effect of adjuvant hyperbaric oxygen therapy on ovarian function after laparoscopic ovarian cystectomy.
UNASSIGNED: A total of 60 patients with ovarian cysts treated at our hospital from January 2018 to August 2020 were enrolled. According to the different treatment modalities, the patients were divided into the control and observation groups. Patients in both groups underwent laparoscopic ovarian cystectomy with oral administration of Chinese patent medicine Kuntai capsules after surgery. Hyperbaric oxygen therapy was added to patients in the observation group in addition to the treatment in the control group. The anti-Müllerian hormone (AMH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), and antral follicle count (AFC) serum levels were detected in both groups before the operation and at the first and third menstrual cycles postoperatively to evaluate ovarian function.
UNASSIGNED: At the first and third menstrual cycles after surgery, the AMH, E2, and AFC serum levels in the two groups were significantly lower than before surgery, and the FSH and LH serum levels were higher than before surgery. The differences were statistically significant (P < 0.05). After the operation, AMH, E2, and AFC serum levels in the observation group were significantly higher than in the control group. FSH and LH serum levels were significantly lower than in the control group, and the differences were statistically significant (P < 0.05).
UNASSIGNED: For patients undergoing laparoscopic ovarian cystectomy, the adjuvant hyperbaric oxygen therapy could significantly improve the postoperative ovarian reserve function with remarkable effects.
摘要:
本研究旨在探讨腹腔镜卵巢囊肿切除术后辅助高压氧治疗对卵巢功能的影响。
共纳入2018年1月至2020年8月在我院治疗的60例卵巢囊肿患者。根据治疗方式的不同,将患者分为对照组和观察组。两组患者均行腹腔镜卵巢囊肿剥除术,术后口服中成药坤泰胶囊。观察组在对照组治疗的基础上增加高压氧治疗。抗苗勒管激素(AMH),卵泡刺激素(FSH),黄体生成素(LH),雌二醇(E2),术前、术后第1次和第3次月经周期检测两组血清窦卵泡计数(AFC)水平,评价卵巢功能。
在手术后的第一个和第三个月经周期,AMH,两组血清E2、AFC程度较术前显著降低,血清FSH和LH水平高于术前。差异有统计学意义(P<0.05)。手术后,AMH,观察组血清E2、AFC水平明显高于对照组。血清FSH和LH水平明显低于对照组,差异均有统计学意义(P<0.05)。
对于接受腹腔镜卵巢囊肿切除术的患者,高压氧辅助治疗能显著改善术后卵巢储备功能,效果显著。
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