METHODS: Based on the inclusion criteria, 15 patients with GAgP were allocated to two groups, group A (before phase I periodontal therapy) and group B (after phase I periodontal therapy). After 3 months, clinical parameters and hematological parameters were reevaluated.
RESULTS: The hematological parameters like hemoglobin (Hb) and red blood cell (RBC) counts were increased significantly after therapy in group B with a significant improvement in the plaque index score, gingival bleeding index score with a reduction of probing depth, and a gain in clinical attachment levels.
CONCLUSIONS: Within the limitation of this study, it could be concluded that GAgP was associated with reduced RBC parameters suggesting that it may tend toward anemia of chronic disease (ACD). Nonsurgical periodontal therapy (NSPT) not only reverses the periodontal health by reducing the inflammation but also improves the anemic status.
CONCLUSIONS: Based on several studies, it was concluded that chronic periodontitis is associated with ACD. This study results indicate that like chronic periodontitis, aggressive periodontitis is also associated with reduced RBC and Hb count suggesting the risk for ACD. So when a patient is diagnosed to have any chronic infectious disease that might lead to ACD, then it is mandatory to treat that particular disease in order to reduce the infection so as to reverse the anemic status of an individual.
方法:根据纳入标准,将15例GAgP患者分为两组,A组(Ⅰ期牙周治疗前)和B组(Ⅰ期牙周治疗后)。三个月后,重新评估了临床参数和血液学参数.
结果:B组治疗后血红蛋白(Hb)和红细胞(RBC)计数等血液学参数明显增加,菌斑指数评分明显改善,牙龈出血指数评分随着探查深度的减少,以及临床依恋水平的提高。
结论:在本研究的范围内,可以得出结论,GAgP与RBC参数降低相关,表明它可能倾向于慢性病贫血(ACD)。非手术牙周治疗(NSPT)不仅可以通过减少炎症来逆转牙周健康,而且可以改善贫血状态。
结论:根据多项研究,结论慢性牙周炎与ACD有关。这项研究结果表明,像慢性牙周炎一样,侵袭性牙周炎还与RBC和Hb计数减少相关,提示发生ACD的风险.因此,当患者被诊断出患有任何可能导致ACD的慢性传染病时,则必须治疗该特定疾病以减少感染,从而逆转个体的贫血状态。