Abstract：
Histiocytic disorders pose significant diagnostic and management challenges for the clinicians due to diverse clinical manifestations and often non-specific histopathologic findings. Herein, we report the tumor board experience from the first-of-its-kind Histiocytosis Working Group (HWG).
The HWG was established in June 2017 and consists of experts from 10 subspecialties that discuss cases in a multidisciplinary format. We present the outcome of tumor board case discussions during the first 2 years since its inception (June 2017-June 2019).
Forty cases with a suspected histiocytic disorder were reviewed at HWG during this time period. Average number of subspecialties involved in HWG case discussion was 5 (range, 2-9). Histiocytosis Working Group tumor board recommendations led to significant changes in the care of 24 (60%) patients. These included change in diagnosis (n = 11, 27%) and change in treatment (n = 13, 33%).
Our report highlights the feasibility of a multidisciplinary tumor board and its impact on outcomes of patients with histiocytic disorders.
The HWG was established in June 2017 and consists of experts from 10 subspecialties that discuss cases in a multidisciplinary format. We present the outcome of tumor board case discussions during the first 2 years since its inception (June 2017-June 2019).
Forty cases with a suspected histiocytic disorder were reviewed at HWG during this time period. Average number of subspecialties involved in HWG case discussion was 5 (range, 2-9). Histiocytosis Working Group tumor board recommendations led to significant changes in the care of 24 (60%) patients. These included change in diagnosis (n = 11, 27%) and change in treatment (n = 13, 33%).
Our report highlights the feasibility of a multidisciplinary tumor board and its impact on outcomes of patients with histiocytic disorders.
摘要：
由于不同的临床表现和通常非特异性的组织病理学发现，组织细胞疾病给临床医生带来了重大的诊断和管理挑战。在这里，我们报告了首次组织细胞增多症工作组(HWG)的肿瘤委员会的经验.
HWG成立于2017年6月，由来自10个分专业的专家组成，以多学科形式讨论病例。我们介绍了肿瘤委员会自成立以来的头两年（2017年6月至2019年6月）的病例讨论结果。
在此期间，HWG对40例疑似组织细胞疾病的病例进行了回顾。HWG病例讨论涉及的亚专业平均数量为5个(范围，2-9).组织细胞增多症工作组肿瘤委员会的建议导致24例（60％）患者的护理发生了重大变化。这些包括诊断的变化（n=11，27％）和治疗的变化（n=13，33％）。
我们的报告强调了多学科肿瘤委员会的可行性及其对组织细胞疾病患者预后的影响。
HWG成立于2017年6月，由来自10个分专业的专家组成，以多学科形式讨论病例。我们介绍了肿瘤委员会自成立以来的头两年（2017年6月至2019年6月）的病例讨论结果。
在此期间，HWG对40例疑似组织细胞疾病的病例进行了回顾。HWG病例讨论涉及的亚专业平均数量为5个(范围，2-9).组织细胞增多症工作组肿瘤委员会的建议导致24例（60％）患者的护理发生了重大变化。这些包括诊断的变化（n=11，27％）和治疗的变化（n=13，33％）。
我们的报告强调了多学科肿瘤委员会的可行性及其对组织细胞疾病患者预后的影响。
