Abstract:
A 30-year-old male diagnosed three years previously with reversible cerebral vasoconstriction syndrome (RCVS) presented to the department of neurology with an accumulation of attacks mimicking previous RCVS attacks and fulfilling the diagnostic criteria for RCVS after receiving the first Pfizer COVID-19 vaccine. The neurologic exam, blood samples, electrocardiogram (ECG), and computer tomography of the head (CTC) were normal. The patient was treated with the angiotensin 2 receptor antagonist, losartan, with a good response and was discharged with a prescription for losartan lasting until three days after the second Pfizer COVID-19 vaccine. No further RCVS attacks were reported. These findings indicate that the COVID-19 vaccine might induce RCVS attacks in susceptible individuals, and targeting the angiotensin 2 receptor could be a preventive option.
摘要:
一名30岁的男性三年前被诊断为可逆性脑血管收缩综合征(RCVS),他在接受了第一支辉瑞COVID-19疫苗后,出现了模仿先前RCVS攻击并符合RCVS诊断标准的攻击。神经系统检查,血液样本,心电图(ECG),头部计算机断层扫描(CTC)正常。患者接受血管紧张素2受体拮抗剂治疗,氯沙坦,反应良好,并在第二次辉瑞COVID-19疫苗接种后三天服用氯沙坦处方出院。没有进一步的RCVS攻击报告。这些结果表明,COVID-19疫苗可能在易感个体中诱导RCVS攻击,靶向血管紧张素2受体可能是一种预防性选择。