Abstract:
Staphylococcus aureus (S. aureus) is a Gram-positive bacterium that may cause life-threatening diseases and some minor infections in living organisms. However, it shows notorious effects when it becomes resistant to antibiotics. Strain variants of bacteria, viruses, fungi, and parasites that have become resistant to existing multiple antimicrobials are termed as superbugs. Methicillin is a semisynthetic antibiotic drug that was used to inhibit staphylococci pathogens. The S. aureus resistant to methicillin is known as methicillin-resistant Staphylococcus aureus (MRSA), which became a superbug due to its defiant activity against the antibiotics and medications most commonly used to treat major and minor infections. Successful MRSA infection management involves rapid identification of the infected site, culture and susceptibility tests, evidence-based treatment, and appropriate preventive protocols. This review describes the clinical management of MRSA pathogenesis, recent developments in rapid diagnosis, and antimicrobial treatment choices for MRSA.
摘要:
金黄色葡萄球菌(S。金黄色葡萄球菌)是一种革兰氏阳性细菌,可能会导致危及生命的疾病和生物体中的一些轻微感染。然而,当它对抗生素产生抗药性时,它表现出臭名昭著的效果。细菌的菌株变体,病毒,真菌,对现有多种抗菌药物产生抗药性的寄生虫被称为超级细菌。甲氧西林是一种半合成抗生素药物,用于抑制葡萄球菌病原体。耐甲氧西林的金黄色葡萄球菌被称为耐甲氧西林金黄色葡萄球菌(MRSA),由于其对抗生素和最常用于治疗主要和次要感染的药物具有反抗活性,因此成为超级细菌。成功的MRSA感染管理包括快速识别感染部位,培养和敏感性试验,循证治疗,和适当的预防方案。本文综述了MRSA发病机制的临床处理,快速诊断的最新进展,MRSA的抗菌治疗选择。