关键词: Antigen receptors Bioinformatics IG Immunoglobulin Pipeline Sequence analysis TR

Mesh : High-Throughput Nucleotide Sequencing Immunoglobulins / genetics Receptors, Antigen, T-Cell / genetics Workflow

来  源:   DOI:10.1007/978-1-0716-2115-8_26

Abstract:
ARResT/Interrogate was built within the EuroClonality-NGS working group to meet the challenge of developing and applying assays for the high-throughput sequence-based profiling of immunoglobulin (IG) and T-cell receptor (TR) repertoires. We herein present basic concepts, outline the main workflow, delve into EuroClonality-NGS-specific aspects, and share insights from our experiences with the platform.
摘要:
ARResT/Interrogate在EuroClonality-NGS工作组内建立,以应对开发和应用用于免疫球蛋白(IG)和T细胞受体(TR)库的高通量基于序列的分析的挑战。我们在此介绍基本概念,概述主要工作流程,深入研究EuroClonality-NGS特定的方面,并通过平台分享我们的经验。
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