Abstract：
Biocompatible, nontoxic, and biodegradable polysaccharides are considered as a promising base for bio-inspired materials, applicable as scaffolds in regenerative medicine, coatings in drug delivery systems, etc. The tunable macroscopic properties of gels should meet case-dependent requirements. The admixture of proteins to polysaccharides and their coupling in more sophisticated structures opens an avenue for gel property tuning via physical cross-linking of components and the modification of gel network structure. In this review recent success in the conformational studies of binary protein-polysaccharide gels is summarized with the main focus upon carrageenans. Future perspectives and challenges in rational design of novel polysaccharide-based materials are outlined.
摘要：
生物相容性,无毒,和可生物降解的多糖被认为是生物启发材料的有前途的基础，适用于再生医学中的支架，药物输送系统中的涂层，等。凝胶的可调宏观性质应满足依赖于情况的要求。蛋白质与多糖的混合以及它们在更复杂的结构中的偶联为通过组分的物理交联和凝胶网络结构的修饰来调节凝胶性质开辟了途径。在这篇综述中，总结了二元蛋白质-多糖凝胶构象研究的最新成功，主要集中在角叉菜胶上。概述了合理设计新型多糖基材料的未来前景和挑战。
