PDF(Pubmed)
Abstract：
Gastric cancer (GC) is the fifth most commonly diagnosed malignancy and the fourth leading cause of cancer death worldwide. Skin metastases from internal organs are rare; skin metastasis from GC occurs even more rarely than skin metastases originating from other organs, and is associated with systematic disease and poor prognosis. The present study described an interesting and rare case of an extensive skin rash in a 42-year-old man diagnosed with GC, which was mainly affecting his left hemithorax, abdomen and back. The rash masqueraded as erysipelas and was initially treated as such; however, it did not respond to antibiotics, corticosteroids and antihistamines. Due to its persistence and location, the rash was biopsied and GC metastasis was confirmed. Third-line chemotherapy was administered and the rash decreased in size; however, the patient suffered from disease deterioration with lung metastases and respiratory failure. The patient eventually died 4 months after the diagnosis of skin metastasis. In conclusion, cutaneous metastasis should be considered as a late and difficult to treat metastasis of GC, which requires high surveillance from medical oncologists, and a multidisciplinary approach for prompt and accurate diagnosis.
摘要：
胃癌（GC）是全球第五大最常见的恶性肿瘤和第四大癌症死亡原因。内脏器官的皮肤转移很少见；GC的皮肤转移比其他器官的皮肤转移更少。并与系统性疾病和不良预后有关。本研究描述了一个有趣且罕见的病例，一名42岁的男性被诊断患有GC，主要影响他的左半胸部，腹部和背部。皮疹伪装成丹毒，最初被如此治疗；然而，它对抗生素没有反应，皮质类固醇和抗组胺药。由于它的持久性和地理位置，对皮疹进行活检，并确认GC转移。进行了三线化疗，皮疹的大小减少；然而，患者病情恶化，肺转移和呼吸衰竭。患者最终在诊断为皮肤转移后4个月死亡。总之,皮肤转移应被认为是一种晚期且难以治疗的GC转移，这需要医学肿瘤学家的高度监测，和多学科的方法，以迅速和准确的诊断。
