关键词: kidney-sparing surgery laser ablation therapy radical nephroureterectomy upper tract urothelial carcinoma urothelial carcinoma

来  源:   DOI:10.33160/yam.2022.05.005   PDF(Pubmed)

Abstract:
Upper tract urothelial carcinoma (UTUC) is a relatively rare disease that accounts for 5% to 10% of all urothelial carcinomas (UCs). Radical nephroureterectomy (RNU) with a bladder cuff is the current gold standard for the management of UTUC; however, endoscopic ablation is also an option for low-risk UTUC to preserve kidney function. Herein, we present two cases of solitary kidney with a right lower ureteral tumor. Both patients underwent left RNU in the past. An 82-year-old man with a right ureteral tumor whose histopathological examination revealed low-grade UC. Laser ablation was performed with ureteroscopy, and there was no recurrence for 7 years after treatment. A 67-year-old woman with a right lower ureteral tumor whose histopathological examination also revealed low-grade UC. Laser ablation was performed, and there was no recurrence for 5 years after the treatment. We closely followed-up our two patients after RNU. This allowed for early detection of tumor recurrence, after which we could perform laser ablation therapy.
摘要:
上尿路上皮癌(UTUC)是一种相对罕见的疾病,占所有尿路上皮癌(UC)的5%至10%。带膀胱袖套的根治性肾输尿管切除术(RNU)是目前治疗UTUC的金标准;然而,内镜消融也是低风险UTUC保护肾功能的一种选择.在这里,我们介绍了2例孤立肾合并右下输尿管肿瘤的病例。两名患者过去都接受了左RNU。一名82岁的男子患有右输尿管肿瘤,其组织病理学检查显示为低度UC。输尿管镜下激光消融,治疗后7年无复发。一名67岁的女性患有右下输尿管肿瘤,其组织病理学检查也显示为低度UC。进行激光烧蚀,治疗后5年无复发。我们密切随访了RNU后的两名患者。这可以早期发现肿瘤复发,之后我们可以进行激光消融治疗。
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