Abstract：
Eosinophilic oesophagitis (EoE) is an increasingly common cause of dysphagia in both children and adults, as well as one of the most prevalent oesophageal diseases with a significant impact on physical health and quality of life. We have provided a single comprehensive guideline for both paediatric and adult gastroenterologists on current best practice for the evaluation and management of EoE.
The Oesophageal Section of the British Society of Gastroenterology was commissioned by the Clinical Standards Service Committee to develop these guidelines. The Guideline Development Group included adult and paediatric gastroenterologists, surgeons, dietitians, allergists, pathologists and patient representatives. The Population, Intervention, Comparator and Outcomes process was used to generate questions for a systematic review of the evidence. Published evidence was reviewed and updated to June 2021. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system was used to assess the evidence and make recommendations. Two rounds of voting were held to assess the level of agreement and the strength of recommendations, with 80% consensus required for acceptance.
Fifty-seven statements on EoE presentation, diagnosis, investigation, management and complications were produced with further statements created on areas for future research.
These comprehensive adult and paediatric guidelines of the British Society of Gastroenterology and British Society of Paediatric Gastroenterology, Hepatology and Nutrition are based on evidence and expert consensus from a multidisciplinary group of healthcare professionals, including patient advocates and patient support groups, to help clinicians with the management patients with EoE and its complications.
The Oesophageal Section of the British Society of Gastroenterology was commissioned by the Clinical Standards Service Committee to develop these guidelines. The Guideline Development Group included adult and paediatric gastroenterologists, surgeons, dietitians, allergists, pathologists and patient representatives. The Population, Intervention, Comparator and Outcomes process was used to generate questions for a systematic review of the evidence. Published evidence was reviewed and updated to June 2021. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system was used to assess the evidence and make recommendations. Two rounds of voting were held to assess the level of agreement and the strength of recommendations, with 80% consensus required for acceptance.
Fifty-seven statements on EoE presentation, diagnosis, investigation, management and complications were produced with further statements created on areas for future research.
These comprehensive adult and paediatric guidelines of the British Society of Gastroenterology and British Society of Paediatric Gastroenterology, Hepatology and Nutrition are based on evidence and expert consensus from a multidisciplinary group of healthcare professionals, including patient advocates and patient support groups, to help clinicians with the management patients with EoE and its complications.
摘要：
嗜酸性粒细胞性食管炎（EoE）是儿童和成人吞咽困难的日益常见的原因，以及最常见的食管疾病之一，对身体健康和生活质量有重大影响。我们为儿科和成人胃肠病学家提供了关于EoE评估和管理的当前最佳实践的单一综合指南。
临床标准服务委员会委托英国胃肠病学会的食道部门制定这些指南。指南发展小组包括成人和儿科胃肠病学家，外科医生,营养师,变态反应学家,病理学家和患者代表。人口,干预,比较和结果过程用于生成问题，以对证据进行系统审查。已发布的证据已审核并更新至2021年6月。建议的分级，评估,使用开发和评估（GRADE）系统来评估证据并提出建议。举行了两轮投票,评估协议的达成程度和建议的力度,接受需要80%的共识。
关于EoE演示文稿的57项声明，诊断,调查,产生了管理和并发症，并就未来研究的领域发表了进一步的声明。
这些英国胃肠病学会和英国儿科胃肠病学会的综合成人和儿科指南，肝病学和营养学基于多学科医疗保健专业人员小组的证据和专家共识，包括患者倡导者和患者支持团体，帮助临床医生管理EoE患者及其并发症。
临床标准服务委员会委托英国胃肠病学会的食道部门制定这些指南。
关于EoE演示文稿的57项声明，
这些英国胃肠病学会和英国儿科胃肠病学会的综合成人和儿科指南，
