关键词: Melissa officinalis L. Valeriana officinalis L attention deficit hyperactivity disorder (ADHD) complementary alternative medicine (CAM) herbal treatments phytotherapy

来  源:   DOI:10.3389/fphar.2022.827411   PDF(Pubmed)

Abstract:
Attention deficit hyperactivity disorder (ADHD) is commonly a neurodevelopmental behavioural disorder in children and adolescents. Mainly characterized by symptoms like lack of attention, hyperactivity, and impulsiveness, it can impact the overall mental development of the one affected. Several factors, both genetic and non-genetic, can be responsible for this disorder. Although several traditional treatment methods involve medication and other counselling techniques, they also come with different side effects. Hence, the choice is now shifting to alternative treatment techniques. Herbal treatments are considered one of the most popular complementary and alternative medicine (CAM) administered. However, issues related to the safety and efficacy of herbal remedies for the treatment of ADHD need to be investigated further. This study aims to find out the recent advancement in evidence-based use of herbal remedies for ADHD by a comprehensive and systematic review that depicts the results of the published works on herbal therapy for the disorder. The electronic databases and the references retrieved from the included studies present related randomized controlled trials (RCTs) and open-label studies. Seven RCTs involving children and adolescents diagnosed with ADHD met the inclusion criteria. There is a fair indication of the efficacy and safety of Melissa officinalis L., Bacopa monnieri (L.) Wettst., Matricaria chamomilla L., and Valeriana officinalis L. from the studies evaluated in this systematic review for the treatment of various symptoms of ADHD. Limited evidence was found for Ginkgo biloba L. and pine bark extract. However, various other preparations from other plants did not show significant efficacy. There is inadequate proof to strongly support and recommend the administration of herbal medicines for ADHD, but more research is needed in the relevant field to popularize the alternative treatment approach.
摘要:
注意缺陷多动障碍(ADHD)通常是儿童和青少年的神经发育行为障碍。主要表现为缺乏注意力等症状,多动症,和冲动,它会影响受影响者的整体心理发展。几个因素,遗传和非遗传,可能是造成这种疾病的原因。尽管一些传统的治疗方法涉及药物和其他咨询技术,它们也有不同的副作用。因此,选择现在正在转向替代治疗技术。草药治疗被认为是最受欢迎的补充和替代医学(CAM)之一。然而,与草药治疗ADHD的安全性和有效性相关的问题需要进一步研究.这项研究旨在通过全面而系统的综述,描述已发表的有关该疾病的草药治疗的成果,以发现基于证据的草药治疗ADHD的最新进展。从纳入的研究中检索到的电子数据库和参考文献提供了相关的随机对照试验(RCT)和开放标签研究。涉及诊断为ADHD的儿童和青少年的七个RCT符合纳入标准。有一个公平的迹象表明的有效性和安全性,Bacopamonnieri(L.)韦特斯特。,洋甘菊,和ValerianaofficinalisL.来自本系统评价中评价的ADHD各种症状的治疗研究。银杏和松树皮提取物的证据有限。然而,来自其他植物的各种其他制剂没有显示出显着的功效。没有足够的证据强烈支持和推荐使用草药治疗多动症,但是需要在相关领域进行更多的研究来推广替代治疗方法。
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