关键词: auricular burn burn chondritis iontophoresis prophylaxis review wound wound care wound healing

Mesh : Anti-Infective Agents, Local Cartilage Diseases / etiology prevention & control Case-Control Studies Humans Inflammation Retrospective Studies

来  源:   DOI:10.12968/jowc.2022.31.5.394

Abstract:
UNASSIGNED: Suppurative chondritis is a potentially devastating complication of burns to the ear. The infection and inflammation can liquify cartilage, leading to significant aesthetic deformities which are difficult to treat. This article reviews published measures for preventing post-burn chondritis.
UNASSIGNED: A comprehensive search of all available literature up to September 2020 was performed, according to PRISMA guidelines, for studies assessing preventive measures for post-burn chondritis. Randomised controlled trials (RCT), cohort studies, case-control studies, case reports and series were eligible for inclusion.
UNASSIGNED: A total of 10 studies, including one RCT and nine retrospective observational analyses, were included, incorporating 1369 patients with burns to the ear. The most common interventions were pressure avoidance (70%), daily cleansing (60%), topical mafenide acetate (60%) and targeted debridement (30%). Packages of measures which included pressure avoidance were the most effective, all of which achieved a chondritis incidence of <6%.
UNASSIGNED: Low-level but strong published evidence suggests that important treatment principles include prevention by pressure relief, targeted debridement, prophylactic local antibiotics, local antisepsis and the avoidance of desiccation.
摘要:
未经证实:化脓性软骨炎是耳朵烧伤的潜在毁灭性并发症。感染和炎症可以液化软骨,导致难以治疗的显著美学畸形。本文回顾了已发表的预防烧伤后软骨炎的措施。
未经评估:对截至2020年9月的所有可用文献进行了全面搜索,根据PRISMA指南,用于评估烧伤后软骨炎预防措施的研究。随机对照试验(RCT),队列研究,病例对照研究,病例报告和系列有资格纳入.
未经评估:共10项研究,包括一项RCT和九项回顾性观察分析,包括在内,合并1369名耳朵烧伤患者。最常见的干预措施是避免压力(70%),每日清洁(60%),局部使用醋酸马菲尼特(60%)和靶向清创术(30%)。包括避免压力的一揽子措施是最有效的,所有这些都达到了软骨炎的发病率<6%。
UNASSIGNED:低水平但强有力的公开证据表明,重要的治疗原则包括通过减压预防,有针对性的清创,预防性局部抗生素,局部防腐和避免干燥。
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