PDF(Pubmed)
Abstract：
UNASSIGNED: To provide a perspective and surgical video demonstration of peripheral corneal ulceration and perforation managed with multilayered amniotic membrane transplantation.
UNASSIGNED: Case 1 describes a 48-year-old female with progressive redness and pain, and an inferonasal corneal thinning and perforation in the left eye from peripheral ulcerative keratitis. She underwent conjunctival recession with amniotic membrane inlay and onlay (Sandwich technique) transplantation. The amniotic membrane integrated well, and her Snellen visual acuity improved from 6/21 preoperatively to 6/9 at 3 months post op. Case 2 describes a 78-year-old male with redness and pain with temporal corneal thinning bilaterally and perforation in the right eye from peripheral ulcerative keratitis. Both eyes underwent similar surgical intervention with smooth integration of the amniotic membrane in the cornea and improvement in the visual acuity. Both patients were also started on systemic immunosuppression in collaboration with the rheumatology team.
UNASSIGNED: We report successful use of multilayered amniotic membrane transplantation for the treatment of corneal ulceration and perforation. The authors believe the simplicity of the surgical technique, easier access to amniotic membrane tissue, and lower induced post-operative astigmatism all provide advantages over alternative treatment modalities.
UNASSIGNED: Case 1 describes a 48-year-old female with progressive redness and pain, and an inferonasal corneal thinning and perforation in the left eye from peripheral ulcerative keratitis. She underwent conjunctival recession with amniotic membrane inlay and onlay (Sandwich technique) transplantation. The amniotic membrane integrated well, and her Snellen visual acuity improved from 6/21 preoperatively to 6/9 at 3 months post op. Case 2 describes a 78-year-old male with redness and pain with temporal corneal thinning bilaterally and perforation in the right eye from peripheral ulcerative keratitis. Both eyes underwent similar surgical intervention with smooth integration of the amniotic membrane in the cornea and improvement in the visual acuity. Both patients were also started on systemic immunosuppression in collaboration with the rheumatology team.
UNASSIGNED: We report successful use of multilayered amniotic membrane transplantation for the treatment of corneal ulceration and perforation. The authors believe the simplicity of the surgical technique, easier access to amniotic membrane tissue, and lower induced post-operative astigmatism all provide advantages over alternative treatment modalities.
摘要：
UNASSIGNED：提供多层羊膜移植治疗周围角膜溃疡和穿孔的透视和手术视频演示。
未经证实：案例1描述了一名48岁女性，患有进行性红肿和疼痛，和周围溃疡性角膜炎的左眼鼻下角膜变薄和穿孔。她接受了羊膜镶嵌和onlay（三明治技术）移植的结膜衰退。羊膜整合良好，她的Snellen视力从术前的6/21提高到术后3个月的6/9。病例2描述了一名78岁的男性，患有周围溃疡性角膜炎的双侧颞侧角膜变薄和右眼穿孔。两只眼睛都进行了类似的手术干预，羊膜在角膜中的平滑整合和视力的改善。两名患者也开始与风湿病团队合作进行全身免疫抑制。
UNASSIGNED：我们报道了多层羊膜移植治疗角膜溃疡和穿孔的成功应用。作者认为手术技术的简单性，更容易接近羊膜组织，和较低的诱发术后散光都提供了优于替代治疗方式的优势。
未经证实：案例1描述了一名48岁女性，患有进行性红肿和疼痛，和周围溃疡性角膜炎的左眼鼻下角膜变薄和穿孔。她接受了羊膜镶嵌和onlay（三明治技术）移植的结膜衰退。羊膜整合良好，她的Snellen视力从术前的6/21提高到术后3个月的6/9。病例2描述了一名78岁的男性，患有周围溃疡性角膜炎的双侧颞侧角膜变薄和右眼穿孔。两只眼睛都进行了类似的手术干预，羊膜在角膜中的平滑整合和视力的改善。两名患者也开始与风湿病团队合作进行全身免疫抑制。
UNASSIGNED：我们报道了多层羊膜移植治疗角膜溃疡和穿孔的成功应用。作者认为手术技术的简单性，更容易接近羊膜组织，和较低的诱发术后散光都提供了优于替代治疗方式的优势。
