PDF(Pubmed)
Abstract：
Proliferative fasciitis (PF) is a rare pseudosarcomatous myofibroblastic benign tumor, a subcutaneous counterpart of proliferative myositis. Usually seen in upper extremities, no case has yet been documented in tongue or any other subsites in oral cavity. The present case becomes the first to be reported at this site as well as the first case of synchronous coexistent PF with squamous cell carcinoma (SCC) of tongue. The patient was 50 years male, having a polypoidal swelling at right lateral border of tongue with an ulcer adjacent to it. Histopathologically, the swelling was diagnosed as PF and ulcer as SCC; both the diagnoses were confirmed by immunohistochemistry. The polypoidal lesion was immunopositive for smooth muscle actin and calponin and immunonegative for pan cytokeratin, cytokeratins (5/6), P40 and P63, proving it to be a non-SCC lesion, different from its adjacent ulcerative one.
摘要：
增生性筋膜炎（PF）是一种罕见的假性肉瘤肌纤维母细胞良性肿瘤，增生性肌炎的皮下对应物。通常见于上肢，尚未在舌头或口腔中的任何其他亚位点记录病例。本病例成为该站点首次报道的病例，也是PF与舌鳞状细胞癌（SCC）同步共存的首例病例。病人是50岁的男性,舌右侧缘有息肉状肿胀，附近有溃疡。组织病理学,肿胀诊断为PF，溃疡诊断为SCC；两种诊断均通过免疫组织化学证实。息肉样病变对平滑肌肌动蛋白和钙蛋白免疫阳性，对泛细胞角蛋白免疫阴性，细胞角蛋白（5/6），P40和P63，证明它是非SCC病变，与其相邻的溃疡性不同。
