PDF(Pubmed)
Abstract：
The aim of this clinical report is to document a rare and unusual case of calcifying odontogenic cyst (COC) in the maxillary anterior region in a 13-year-old girl. A COC is an extremely uncommon developmental, odontogenic entity and accounts for 0.3%-0.8% of odontogenic cysts. The lesion presents as an array of varied radiographic and clinicopathological characteristics and biological attributes and exists in three histomorphologic patterns - benign cystic, solid (neoplastic) and aggressive (malignant) forms. Thus, several nomenclatures and classifications have been put forth to explain the nature of the clinical entity. However, ambiguities regarding the exact nature of the lesion still prevail. Due to nonspecific clinicoradiographic features, histopathological interpretation remains the key for diagnosis. We report an uncommon occurrence of COC in a 13-year-old female who reported to our Outpatient Department with an asymptomatic right midfacial swelling. The clinical and radiographic findings were suggestive of adenomatoid odontogenic tumor and dentigerous cyst. The decision to enucleate the lesion was considered, and histopathological features were compatible with the diagnosis of COC. Re-ossification with no recurrence was noticed after a 1-year follow-up. COC is an unusual developmental odontogenic cyst that clinically and radiologically simulates other more common jaw entities. Thorough knowledge of the bizarre presentation and biological attributes of such lesions are imperative for an early diagnosis and definitive treatment. Long-term follow-up is advocated to prevent recurrences.
摘要：
本临床报告的目的是记录一名13岁女孩上颌前区钙化牙源性囊肿（COC）的罕见病例。COC是一个非常不寻常的发展，牙源性实体，占牙源性囊肿的0.3%-0.8%。病变表现为一系列不同的放射学和临床病理特征和生物学属性，并存在三种组织形态学模式-良性囊性，实体（肿瘤）和侵袭性（恶性）形式。因此，已经提出了一些术语和分类来解释临床实体的性质。然而,关于病变的确切性质的歧义仍然普遍存在。由于非特异性的临床影像学特征，组织病理学解释仍然是诊断的关键。我们报告了一名13岁女性的COC罕见情况，该女性向我们的门诊部报告无症状的右面部中部肿胀。临床和影像学检查结果考虑腺瘤样牙源性肿瘤和牙源性囊肿。考虑了摘除病变的决定，组织病理学特征与COC的诊断相符。随访1年，发现骨化复发。COC是一种不寻常的发育牙源性囊肿，可在临床和放射学上模拟其他更常见的下颌实体。全面了解此类病变的奇异表现和生物学属性对于早期诊断和明确治疗至关重要。提倡长期随访以防止复发。
