Abstract：
Background: Phototherapy is one of the treatments for vitiligo. To be specific, the combination of narrowband ultraviolet B (NB-UVB) with topical preparations has currently become the most common therapeutic modality. Moreover, the research on new topical drug has been a hot issue in the field of vitiligo. Objective: At present, simvastatin has been considered as a potential therapeutic agent for the treatment of vitiligo. To the best of our knowledge, this is the first case report concerning the successful application of NB-UVB combined with topical simvastatin in the treatment of vitiligo. Methods: In this article, a clinical case report was presented, where the patient was not responsive to NB-UVB but was markedly responsive to the treatment of UVB combined with topical simvastatin. Results: A 34-year-old Chinese female patient with vitiligo was cured by NB-UVB combined with topical simvastatin solution. Conclusions: NB-UVB combined with topical simvastatin may be a potential treatment against vitiligo. This research was approved by the Medical Ethics Committee of Third People\'s Hospital of Hangzhou.
摘要：
背景：光疗是白癜风的治疗方法之一。具体而言,窄带紫外线B（NB-UVB）与局部制剂的组合目前已成为最常见的治疗方式。此外，新型外用药物的研究一直是白癜风治疗领域的热点。目的:目前,辛伐他汀被认为是治疗白癜风的潜在治疗剂。据我们所知,这是首例成功应用NB-UVB联合外用辛伐他汀治疗白癜风的病例报告。方法：在本文中，提交了一份临床病例报告，患者对NB-UVB无反应，但对UVB联合局部辛伐他汀治疗有明显反应。结果：1例34岁的中国女性白癜风患者经NB-UVB联合辛伐他汀溶液外用治愈。结论:NB-UVB联合辛伐他汀外用治疗白癜风可能是一种潜在的治疗方法。本研究获得杭州市第三人民医院医学伦理委员会批准。
