Abstract：
Diabetes mellitus is an established risk factor for acute myocardial infarction (AMI). Incidence of AMI in people with diabetes remains significantly higher than in those without diabetes. However, published data are conflicting, and previous reviews in this field have some limitations regarding the definitions of AMI and source population (general population or people with diabetes as a population at risk) and concerning the statistical presentation of results.
To analyse the incidence of AMI in people with diabetes compared to those without diabetes and to investigate time trends.
We will perform a systematic literature search in MEDLINE, Embase and LILACS designed by an experienced information scientist. Two review authors will independently screen the abstracts and full texts of all references on the basis of inclusion criteria regarding types of study, types of population and the main outcome. Data extraction and assessment of risk of bias will be undertaken by two review authors working independently. We will assess incidence rate or cumulative incidence and relative risk of AMI comparing populations with and without diabetes.
This review will summarise the available data concerning the incidence of AMI in people with and without diabetes and will thus contribute to the assessment and interpretation of the wide variations of incidence, relative risks and time trends of AMI in these populations.
PROSPERO CRD42020145562.
To analyse the incidence of AMI in people with diabetes compared to those without diabetes and to investigate time trends.
We will perform a systematic literature search in MEDLINE, Embase and LILACS designed by an experienced information scientist. Two review authors will independently screen the abstracts and full texts of all references on the basis of inclusion criteria regarding types of study, types of population and the main outcome. Data extraction and assessment of risk of bias will be undertaken by two review authors working independently. We will assess incidence rate or cumulative incidence and relative risk of AMI comparing populations with and without diabetes.
This review will summarise the available data concerning the incidence of AMI in people with and without diabetes and will thus contribute to the assessment and interpretation of the wide variations of incidence, relative risks and time trends of AMI in these populations.
PROSPERO CRD42020145562.
摘要：
糖尿病是急性心肌梗死（AMI）的既定危险因素。糖尿病患者的AMI发病率仍然明显高于非糖尿病患者。然而,公布的数据相互矛盾，和以前在该领域的综述在AMI和来源人群(普通人群或糖尿病患者作为高危人群)的定义以及结果的统计表示方面有一些局限性。
分析糖尿病患者与无糖尿病患者的AMI发病率，并调查时间趋势。
我们将在MEDLINE进行系统的文献检索，Embase和LILACS由经验丰富的信息科学家设计。两位综述作者将根据关于研究类型的纳入标准，独立筛选所有参考文献的摘要和全文，人口类型和主要结果。数据提取和偏见风险评估将由两名独立工作的评论作者进行。我们将比较有和没有糖尿病的人群，评估AMI的发病率或累积发病率和相对风险。
这篇综述将总结有关糖尿病患者和非糖尿病患者AMI发病率的现有数据，从而有助于评估和解释发病率的广泛变化。这些人群中AMI的相对风险和时间趋势。
PROSPEROCRD42020145562。
分析糖尿病患者与无糖尿病患者的AMI发病率，并调查时间趋势。
我们将在MEDLINE进行系统的文献检索，Embase和LILACS由经验丰富的信息科学家设计。两位综述作者将根据关于研究类型的纳入标准，独立筛选所有参考文献的摘要和全文，人口类型和主要结果。数据提取和偏见风险评估将由两名独立工作的评论作者进行。我们将比较有和没有糖尿病的人群，评估AMI的发病率或累积发病率和相对风险。
这篇综述将总结有关糖尿病患者和非糖尿病患者AMI发病率的现有数据，从而有助于评估和解释发病率的广泛变化。这些人群中AMI的相对风险和时间趋势。
PROSPEROCRD42020145562。
