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Abstract：
UNASSIGNED: Spontaneous bacterial peritonitis (SBP) is a bacterial infection associated with a high mortality rate in cirrhotic patients. The gold standard for the detection of SBP is a manual cell count from ascitic fluid; however, alternative screening methods are under investigation. In particular, leukocyte esterase reagent strips (LERS) has been studied as an alternative method to detect SBP with a low cost and instant turnaround time. Therefore, this study aims to evaluate the performance of LERS in the detection of SBP.
UNASSIGNED: A literature search was performed for studies evaluating LERS for the detection of SBP on PubMed, Embase, Scopus, Cochrane, and clinical trial registries. Summary sensitivity, specificity, log diagnostic odds ratio (LDOR), and the area under the summary receiver operating curve (AUC) were calculated according to the respective manufacturer.
UNASSIGNED: In total, 31 studies were evaluated. The summary sensitivity of Aution Sticks, Combur, Multistix, Periscreen reagent strips was 0.962 (95% confidence interval [CI] 0.926, 0.998), 0.892 (95% CI 0.846, 0.938), 0.806 (95% CI 0.738, 0.874), and 0.939 (95% CI 0.900, 0.979), respectively. The summary specificity of Aution Sticks, Combur, Multistix, and Periscreen reagent strips was 0.940 (95% CI 0.904, 0.976), 0.922 (95% CI 0.874, 0.970), 0.974 (95% CI 0.962, 0.985), and 0.672 (95% CI 0.381, 0.963), respectively.
UNASSIGNED: LERS appears to have a notable overall performance for the detection of SBP. LERS appeared to be an acceptable alternative to diagnose SBP in facilities without ability to perform cell count. However, there were significant differences in performance between each manufacturer.
UNASSIGNED: A literature search was performed for studies evaluating LERS for the detection of SBP on PubMed, Embase, Scopus, Cochrane, and clinical trial registries. Summary sensitivity, specificity, log diagnostic odds ratio (LDOR), and the area under the summary receiver operating curve (AUC) were calculated according to the respective manufacturer.
UNASSIGNED: In total, 31 studies were evaluated. The summary sensitivity of Aution Sticks, Combur, Multistix, Periscreen reagent strips was 0.962 (95% confidence interval [CI] 0.926, 0.998), 0.892 (95% CI 0.846, 0.938), 0.806 (95% CI 0.738, 0.874), and 0.939 (95% CI 0.900, 0.979), respectively. The summary specificity of Aution Sticks, Combur, Multistix, and Periscreen reagent strips was 0.940 (95% CI 0.904, 0.976), 0.922 (95% CI 0.874, 0.970), 0.974 (95% CI 0.962, 0.985), and 0.672 (95% CI 0.381, 0.963), respectively.
UNASSIGNED: LERS appears to have a notable overall performance for the detection of SBP. LERS appeared to be an acceptable alternative to diagnose SBP in facilities without ability to perform cell count. However, there were significant differences in performance between each manufacturer.
摘要：
未经证实：自发性细菌性腹膜炎（SBP）是一种与肝硬化患者高死亡率相关的细菌感染。检测SBP的金标准是从腹水中手动计数细胞；然而，正在研究其他筛查方法。特别是,已经研究了白细胞酯酶试剂条（LERS）作为低成本和即时周转时间检测SBP的替代方法。因此,本研究旨在评估LERS在SBP检测中的性能。
UNASSIGNED：对评估LERS在PubMed上检测SBP的研究进行了文献检索，Embase,Scopus,科克伦,和临床试验注册。Summarysensitivity,特异性，对数诊断优势比(LDOR)，和根据各自的制造商计算总接受者工作曲线下面积(AUC)。
未经批准：总共，评估了31项研究。解决方案棒的概要灵敏度，Combur,Multistix,Periscreen试剂条为0.962（95%置信区间[CI]0.926，0.998），0.892（95%CI0.846，0.938），0.806（95%CI0.738，0.874），和0.939（95%CI0.900，0.979），分别。解决方案棒的总结特异性，Combur,Multistix,Periscreen试剂条为0.940（95%CI0.904，0.976），0.922（95%CI0.874，0.970），0.974（95%CI0.962，0.985），和0.672（95%CI0.381，0.963），分别。
未经证实：LERS在检测SBP方面似乎具有显著的整体性能。在没有细胞计数能力的设施中，LERS似乎是诊断SBP的可接受的替代方法。然而,每个制造商之间的性能存在显著差异.
UNASSIGNED：对评估LERS在PubMed上检测SBP的研究进行了文献检索，
未经批准：总共，
未经证实：LERS在检测SBP方面似乎具有显著的整体性能。
