Ketamine-induced uropathy: A diagnostic pitfall in an increasing healthcare issue in youngsters.

氯胺酮引起的尿路病变 ： 青少年医疗保健问题日益严重的诊断陷阱。

• 发表时间: May 2022
• 来源期刊: Urol Case Rep
• DOI: 10.1016/j.eucr.2022.102019
• PMID: 35530548
• 文章类型: Case Reports
• 作者列表: Lamers G,Van Dyck J,Schapmans S,De Coster K,Mortier D,Zabegalina N

关键词: ADHD, Attention-deficit/hyperactivity disorder; BPS, bladder pain syndrome; Bladder; CRP, C-reactive protein; IV, intravenous; KIU, ketamine induced uropathy; Ketamine; LUTS; LUTS, lower urinary tract symptoms; NMDA, N-Methyl-d-aspartate; STD, sexual transmitted disease; UTI, urinary tract infection; Uropathy; hpf, high power field

Abstract

Ketamine induced uropathy (KIU) is a urological condition increasing in prevalence, with similar symptoms to UTI, OAB syndrome or interstitial cystitis/bladder pain syndrome. We present the case of an 18-year old male who established severe LUTS and acute kidney injury due to KIU, in a short time-span of 6 months. Since cessation of ketamine is the cornerstone of treating KIU, correct and early diagnosis is essential. Physicians should therefore consider KIU as a differential diagnosis in storage LUTS, especially in younger patients with therapy-resistant LUTS.

摘要

氯胺酮诱发的尿路病变（KIU）是一种患病率增加的泌尿系统疾病，与UTI症状相似,OAB综合征或间质性膀胱炎/膀胱疼痛综合征。我们介绍了一个18岁的男性，由于KIU导致严重的LUTS和急性肾损伤，在短短的6个月内。由于停止氯胺酮是治疗KIU的基石，正确和早期诊断至关重要。因此，医师应将KIU视为储存LUTS的鉴别诊断，尤其是在治疗耐药的LUTS年轻患者中。