PDF(Pubmed)
Abstract：
UNASSIGNED: Lagophthalmos with exposure keratopathy is a potential vision-threatening complication following surgery for blepharoptosis. We report three cases successfully treated with botulinum toxin-A (Botox®, Allergan, Irvine, USA) for this complication.
UNASSIGNED: Three patients presented with severe blepharoptosis after surgery for orbital and frontal base tumors. They obtained good appearances after frontalis-orbicularis oculi muscle (FOOM) flap shortening. However, exposure keratopathy developed after the surgery despite frequent use of topical lubricants and autologous serum eye drops. We injected 5-10 units of botulinum toxin-A around the central supra-brow area, which was near the origin of the FOOM flap. One week later, they developed ptosis and could close the eye completely. The corneal defect gradually resolved. They recovered from ptosis 3 months later and never required a second injection.
UNASSIGNED: Lagophthalmos with exposure keratopathy is a potential vision-threatening complication following FOOM flap surgery. In severe cases, surgical revision should be considered to partially or totally release the FOOM flap attachment, which also decreases its function permanently. In this case series, we demonstrated that injecting botulinum toxin-A may be a promising method to manage this complication without permanently affecting the function of the FOOM flap.
UNASSIGNED: A botulinum toxin-A injection may be an effective treatment for patients developing exposure keratopathy after FOOM flap surgery.
UNASSIGNED: Three patients presented with severe blepharoptosis after surgery for orbital and frontal base tumors. They obtained good appearances after frontalis-orbicularis oculi muscle (FOOM) flap shortening. However, exposure keratopathy developed after the surgery despite frequent use of topical lubricants and autologous serum eye drops. We injected 5-10 units of botulinum toxin-A around the central supra-brow area, which was near the origin of the FOOM flap. One week later, they developed ptosis and could close the eye completely. The corneal defect gradually resolved. They recovered from ptosis 3 months later and never required a second injection.
UNASSIGNED: Lagophthalmos with exposure keratopathy is a potential vision-threatening complication following FOOM flap surgery. In severe cases, surgical revision should be considered to partially or totally release the FOOM flap attachment, which also decreases its function permanently. In this case series, we demonstrated that injecting botulinum toxin-A may be a promising method to manage this complication without permanently affecting the function of the FOOM flap.
UNASSIGNED: A botulinum toxin-A injection may be an effective treatment for patients developing exposure keratopathy after FOOM flap surgery.
摘要：
未经证实：隐眼性角膜病变是上睑下垂手术后潜在的视力威胁并发症。我们报告了三例成功使用肉毒杆菌毒素A（Botox®，Allergan,Irvine,美国）对于这种并发症。
未经授权：3例患者在眼眶和额叶基部肿瘤手术后出现严重上睑下垂。额叶-眼轮匝肌（FOOM）皮瓣缩短后，它们获得了良好的外观。然而,尽管经常使用局部润滑剂和自体血清滴眼液，但手术后仍出现暴露性角膜病变。我们在中央眉上区域周围注射了5-10单位的肉毒杆菌毒素A，靠近FOOM皮瓣的起源。一周后,他们出现了眼睑下垂，可以完全闭上眼睛。角膜缺损逐渐解决。3个月后，他们从眼睑恢复，从未需要第二次注射。
UNASSIGNED：隐眼角膜病变是FOOM皮瓣手术后潜在的视力威胁并发症。在严重的情况下,手术翻修应考虑部分或完全释放FOOM皮瓣附件，这也会永久降低其功能。在这个系列中,我们证明,注射A型肉毒杆菌毒素可能是治疗这种并发症的一种有前景的方法,而不会永久影响FOOM皮瓣的功能.
UNASSIGNED：对于FOOM皮瓣手术后发生暴露性角膜病变的患者，A肉毒杆菌毒素注射可能是一种有效的治疗方法。
未经授权：3例患者在眼眶和额叶基部肿瘤手术后出现严重上睑下垂。额叶-眼轮匝肌（FOOM）皮瓣缩短后，它们获得了良好的外观。然而,尽管经常使用局部润滑剂和自体血清滴眼液，但手术后仍出现暴露性角膜病变。我们在中央眉上区域周围注射了5-10单位的肉毒杆菌毒素A，靠近FOOM皮瓣的起源。一周后,他们出现了眼睑下垂，可以完全闭上眼睛。角膜缺损逐渐解决。3个月后，他们从眼睑恢复，从未需要第二次注射。
UNASSIGNED：隐眼角膜病变是FOOM皮瓣手术后潜在的视力威胁并发症。在严重的情况下,手术翻修应考虑部分或完全释放FOOM皮瓣附件，这也会永久降低其功能。在这个系列中,我们证明,注射A型肉毒杆菌毒素可能是治疗这种并发症的一种有前景的方法,而不会永久影响FOOM皮瓣的功能.
UNASSIGNED：对于FOOM皮瓣手术后发生暴露性角膜病变的患者，A肉毒杆菌毒素注射可能是一种有效的治疗方法。
