关键词: Ex vivo lung perfusion Lung transplantation Organ donation Specialized donor care facility Ex vivo lung perfusion Lung transplantation Organ donation Specialized donor care facility

Mesh : Extracorporeal Circulation Humans Lung Lung Transplantation / methods Organ Preservation / methods Perfusion / methods Tissue Donors Tissue and Organ Procurement

来  源:   DOI:10.1016/j.thorsurg.2021.11.003

Abstract:
An increased focus on improving efficiency and decreasing costs has resulted in alternative models of donor management and organ recovery. The specialized donor care facility model provides highly efficient and cost-effective donor care at a free-standing facility, resulting in improved organ yield, shorter ischemic times, decreased travel, and fewer nighttime operations. Ex vivo lung perfusion (EVLP) improves utilization of extended criteria donor lungs, and centralized EVLP facilities have the potential to increase transplant volumes for smaller transplant programs in specified geographic regions. These alternative models are increasingly being used in the United States to improve waitlist mortality and combat the ongoing donor organ shortage.
摘要:
对提高效率和降低成本的日益关注导致了供体管理和器官恢复的替代模式。专门的捐献者护理机构模式在独立机构提供高效率和高成本效益的捐献者护理,导致器官产量提高,缺血时间较短,旅行减少,和更少的夜间操作。离体肺灌注(EVLP)提高了扩展标准供体肺的利用率,和集中式EVLP设施有可能增加特定地理区域中较小移植程序的移植量。这些替代模型在美国越来越多地用于提高候补死亡率并应对持续的供体器官短缺。
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