关键词: National Health and Nutrition Examination Survey all-cause mortality cancer/malignant neoplasms mortality dose–response relationship heart disease mortality water intake

来  源:   DOI:10.3389/fnut.2022.822119   PDF(Pubmed)

Abstract:
UNASSIGNED: Few studies have explored the association between water intake and mortality risk, and the findings were inconsistent.
UNASSIGNED: This study aimed to explore the water intake-mortality association, utilizing the data from the National Health and Nutrition Examination Survey (NHANES) and the 2015 public-linked mortality files released by the National Center for Health Statistics.
UNASSIGNED: We used the diet- and mortality-linked data of a total of 35,463 adults (17,234 men) aged ≥20 years in the NHANESs 1999-2014 to perform a prospective study. The multivariate-adjusted Cox proportional hazards model was used to explore the associations of the amount of water intake (expressed by total water, plain water, beverage, and food water) and water intake proportion (expressed by the percentage of each kind of water) with mortality risks due to all causes, malignant neoplasms/cancer, and heart disease. The restricted cubic spline plots were adopted to clarify the dose-response relationships among them.
UNASSIGNED: With a median of 88 months (interquartile range: 49-136 months) follow-up, a total of 4,915 all-cause deaths occurred, including 1,073 and 861 deaths from malignant neoplasms/cancer and heart disease, respectively. The amount of water intake in either type was negatively associated with all-cause mortality risk. Additionally, the negative linear dose-response relationships of water intake and all-cause mortality risk were found for all types of water except for food water, which followed a non-linear pattern. Similarly, compared to the lowest quartile (beverage water intake: <676 g/day; food water intake: <532 g/day), beverage and food water intakes in the range of 1,033-1,524 and 1,612-3,802 g/day were associated with decreased malignant neoplasms/cancer mortality risk. A U-shaped dose-response relationship was found for beverage water intake and malignant neoplasms/cancer mortality risk and a negative linear dose-response relationship was found for food water intake and malignant neoplasms/cancer mortality risk. Coffee and/or tea consumption was/were negatively associated with mortality risks due to all causes and malignant neoplasms/cancer. No significant associations of water intake proportion and mortality risks were found.
UNASSIGNED: Our findings demonstrated that higher water intake is associated with lower mortality risks among the United States population.
摘要:
未经评估:很少有研究探讨水摄入量与死亡风险之间的关系,和调查结果是不一致的。
未经评估:本研究旨在探讨水摄入量与死亡率的关系,利用国家健康和营养检查调查(NHANES)和国家卫生统计中心发布的2015年与公众相关的死亡率文件的数据。
UNASSIGNED:我们使用1999-2014年NHANESs中年龄≥20岁的35,463名成年人(17,234名男性)的饮食和死亡率相关数据进行前瞻性研究。多变量调整后的Cox比例风险模型用于探索水摄入量(以总水量表示,平原水,饮料,和食物水)和水的摄入量比例(以每种水的百分比表示),由于各种原因而具有死亡风险,恶性肿瘤/癌症,还有心脏病.采用有限的三次样条图来阐明它们之间的剂量-反应关系。
UNASSIGNED:中位随访88个月(四分位距:49-136个月),共发生全因死亡4915例,包括1,073人和861人死于恶性肿瘤/癌症和心脏病,分别。两种类型的饮水量与全因死亡风险呈负相关。此外,除食物水外,所有类型的水都发现了水摄入量和全因死亡风险的负线性剂量-反应关系,遵循非线性模式。同样,与最低四分位数相比(饮料水摄入量:<676克/天;食物水摄入量:<532克/天),1,033-1,524和1,612-3,802克/天的饮料和食物水摄入量与降低恶性肿瘤/癌症死亡风险相关.发现饮料水摄入量和恶性肿瘤/癌症死亡风险呈U形剂量反应关系,而食物水摄入量和恶性肿瘤/癌症死亡风险呈负线性剂量反应关系。由于各种原因和恶性肿瘤/癌症,咖啡和/或茶的消费与死亡风险呈负相关。没有发现水的摄入比例和死亡风险的显着关联。
UNASSIGNED:我们的研究结果表明,在美国人口中,较高的水摄入量与较低的死亡风险相关。
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