A superconducting quantum interference device magnetometer system was used to record neuromagnetic fields at the carpal tunnel after electrical stimulation of the middle digital nerve in 10 hands of nine patients with carpal tunnel syndrome. The patients were diagnosed based on symptoms (numbness, tingling, and pain) supported by a positive Phalen or Tinel sign. A novel technique was applied to remove stimulus-induced artifacts, and current distributions were calculated using a spatial filter algorithm and superimposed on X-ray.
In 6 of the 10 hands, the amplitude of the inward current waveform attenuated to <70% or the nerve conduction velocity was <40 m/s. The results of conventional nerve conduction studies were normal for two of these six hands. All four hands that could not be diagnosed by magnetoneurography had severe carpal tunnel syndrome superimposed on peripheral neuropathy secondary to comorbidities.
Technical improvements enabled magnetoneurography to noninvasively visualize the electrophysiological nerve activity in carpal tunnel syndrome patients.
Magnetoneurography may have the potential to contribute to the detailed diagnosis of various peripheral nerve disorders.
使用超导量子干扰设备磁力计系统记录了9名腕管综合征患者的10只手中指神经电刺激后腕管的神经磁场。根据症状(麻木,刺痛,和疼痛)由Phalen或Tinel阳性体征支持。一种新的技术被用来去除刺激引起的伪影,和电流分布是使用空间滤波算法计算的,并叠加在X射线上。
10只手中的6只手,内向电流波形的幅度衰减至<70%或神经传导速度<40m/s。常规神经传导研究的结果对于这六只手中的两只是正常的。无法通过磁神经描记术诊断的所有四只手都患有严重的腕管综合征,并伴有继发于合并症的周围神经病变。
技术改进使得磁神经描记术能够无创地观察腕管综合征患者的神经电生理活动。
磁神经成像可能有助于各种周围神经疾病的详细诊断。