Abstract：
Negative psychotic symptoms are among the most disabling features of schizophrenia, and are strongly associated with relatively poor clinical and functional outcomes. However, there are no effective treatments for negative symptoms, and this represents a major unmet clinical need. Recent research has shown that negative symptoms are already present in many patients at illness onset. There is evidence that cariprazine may improve negative symptoms in patients with chronic schizophrenia. However, its utility in treating negative symptoms in the early stage of the disorder is unclear. Here, we report six cases of patients with first-episode psychosis who were treated with cariprazine.
摘要：
消极的精神病症状是精神分裂症最致残的特征之一，并且与相对较差的临床和功能结局密切相关。然而,阴性症状没有有效的治疗方法，这代表了一个主要的未满足的临床需求。最近的研究表明，许多患者在发病时已经出现阴性症状。有证据表明卡利拉嗪可以改善慢性精神分裂症患者的阴性症状。然而,它在治疗疾病早期阴性症状中的效用尚不清楚。这里,我们报告了6例首发精神病患者接受卡利拉嗪治疗的病例.
