关键词: Dermatology HIV, human immunodeficiency virus HSV, herpes simplex virus Herpes simplex virus (HSV) Herpes vegetans Infectious Disease NMSC, nonmelanoma skin cancer Nonmelanoma skin cancer (NMSC) PCR, polymerase-chain reaction VZV, varicella zoster virus

来  源:   DOI:10.1016/j.idcr.2022.e01502   PDF(Pubmed)

Abstract:
Atypical morphologic and anatomic presentations of herpetic infection can be a diagnostic and therapeutic challenge. Although herpes simplex virus type 2 (HSV-2) infections primarily occur in the oral or anogenital region, our patient presented with ulcerated vegetative plaques on the shoulder sharing clinical features with nonmelanoma skin cancer (NMSC). Depending on the clinical appearance and anatomical site, proper workup including biopsy can be pivotal to arrive at a correct diagnosis as lesions can mimic a broad spectrum of cutaneous diseases, particularly if the lesion occurs in an atypical location. Dermatology providers should include HSV-2 in the differential diagnosis when challenged with unusual ulcerated or verrucous lesions.
摘要:
疱疹感染的不典型形态和解剖表现可能是诊断和治疗挑战。虽然单纯疱疹病毒2型(HSV-2)感染主要发生在口腔或生殖器区域,我们的患者表现为肩关节上的溃疡营养斑与非黑色素瘤皮肤癌(NMSC)具有共同的临床特征.根据临床表现和解剖部位,包括活组织检查在内的适当检查对于获得正确的诊断至关重要,因为病变可以模仿广谱的皮肤病,特别是如果病变发生在不典型的位置。皮肤科提供者在有异常溃疡或疣状病变时,应将HSV-2纳入鉴别诊断。
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