PDF(Pubmed)
Abstract：
UNASSIGNED: Narrowband UVB (NB UVB) has been suggested as an option for lichen planus control. However, the literature is lacking in reports of long-term results. OBJECTIVE: We sought to evaluate the long-term results of NB UVB therapy in lichen planus.
UNASSIGNED: This was a prospective, retrospective analysis of patients with lichen planus treated with NB UVB at our institution since 2004. The clinical response and relapse rate were recorded according to age, sex, mouth involvement, skin phototype, number of treatments, and total radiation dose.
UNASSIGNED: One hundred thirty-seven of 192 (71%) eligible patients had a major response (MR) and 102 (74%) patients had no recurrence after an average follow-up period of 58.7 months. MR was achieved in 66 percent and 75 percent of men and women, respectively (p=0.021) and 76 percent and 68 percent of patients with Fitzpatrick Skin Types I and II and Skin Types IV and V, respectively (p=0.017). Age at the onset of the disease, number of treatments, and total UVB dose had no effect on the MR rate. The disease-free periods were 131 and 101 months for male and female patients, respectively (p=0.06), and 128 and 103 months for patients 40 years or younger and older than 40 years of age, respectively (p=0.07).
UNASSIGNED: Based on our results, female patients and patients with lighter skin phototypes appeared to have higher MR rates. However, female and older patients appear to be at increased risk of recurrence.
UNASSIGNED: This was a prospective, retrospective analysis of patients with lichen planus treated with NB UVB at our institution since 2004. The clinical response and relapse rate were recorded according to age, sex, mouth involvement, skin phototype, number of treatments, and total radiation dose.
UNASSIGNED: One hundred thirty-seven of 192 (71%) eligible patients had a major response (MR) and 102 (74%) patients had no recurrence after an average follow-up period of 58.7 months. MR was achieved in 66 percent and 75 percent of men and women, respectively (p=0.021) and 76 percent and 68 percent of patients with Fitzpatrick Skin Types I and II and Skin Types IV and V, respectively (p=0.017). Age at the onset of the disease, number of treatments, and total UVB dose had no effect on the MR rate. The disease-free periods were 131 and 101 months for male and female patients, respectively (p=0.06), and 128 and 103 months for patients 40 years or younger and older than 40 years of age, respectively (p=0.07).
UNASSIGNED: Based on our results, female patients and patients with lighter skin phototypes appeared to have higher MR rates. However, female and older patients appear to be at increased risk of recurrence.
摘要：
UNASSIGNED：窄带UVB（NBUVB）已被建议作为扁平苔藓控制的一种选择。然而,文献缺乏长期结果的报道。目的：我们试图评估NBUVB治疗扁平苔藓的长期效果。
未经批准：这是一个潜在的，回顾性分析自2004年以来在我们机构接受NBUVB治疗的扁平苔藓患者。根据年龄记录临床反应和复发率，性别,口腔参与，皮肤照型，治疗次数,和总辐射剂量。
UNASSIGNED：192名合格患者中有127名（71％）有主要反应（MR），102名（74％）患者在平均随访期为58.7个月后没有复发。66％和75％的男性和女性实现了MR，Fitzpatrick皮肤类型I和II以及皮肤类型IV和V的患者分别为（p=0.021）和76％和68％，分别(p=0.017)。发病时的年龄，治疗次数,总UVB剂量对MR率无影响。男性和女性患者的无病期分别为131和101个月，分别为（p=0.06），40岁或更小和40岁以上的患者为128个月和103个月，分别(p=0.07)。
未经评估：根据我们的结果，女性患者和皮肤光型较浅的患者的MR率较高.然而,女性和老年患者的复发风险增加.
未经批准：这是一个潜在的，回顾性分析自2004年以来在我们机构接受NBUVB治疗的扁平苔藓患者。根据年龄记录临床反应和复发率，性别,口腔参与，皮肤照型，治疗次数,和总辐射剂量。
UNASSIGNED：192名合格患者中有127名（71％）有主要反应（MR），102名（74％）患者在平均随访期为58.7个月后没有复发。66％和75％的男性和女性实现了MR，Fitzpatrick皮肤类型I和II以及皮肤类型IV和V的患者分别为（p=0.021）和76％和68％，分别(p=0.017)。发病时的年龄，治疗次数,总UVB剂量对MR率无影响。男性和女性患者的无病期分别为131和101个月，分别为（p=0.06），40岁或更小和40岁以上的患者为128个月和103个月，分别(p=0.07)。
未经评估：根据我们的结果，女性患者和皮肤光型较浅的患者的MR率较高.然而,女性和老年患者的复发风险增加.
