关键词: ANA, Anti-nuclear antibodies Conjunctival chemosis Conjunctival injection DIV, Drug-induced vasculitis HSV, Herpes simplex virus Hydralazine Vasculitis c-ANCA, cytoplasmic antineutrophil cytoplasmic antibody p-ANCA, perinuclear antineutrophil cytoplasmic antibody

来  源:   DOI:10.1016/j.ajoc.2022.101515   PDF(Pubmed)

Abstract:
UNASSIGNED: The objective of the study is to report a case of ocular manifestations in a patient with hydralazine-induced vasculitis.
UNASSIGNED: An 88-year-old female was admitted for lower gastrointestinal bleeding. Nine days after admission, she developed bilateral conjunctival chemosis and injection, which rapidly progressed into grouped blistering eruptions of the periorbital skin, face, and neck. After extensive testing and evaluation, her constellation of findings was diagnosed as hydralazine-induced vasculitis. Treatment with intravenous steroids and discontinuation of hydralazine resulted in improvement of the cutaneous and ocular manifestations. Herein we describe the clinical course of an adult patient with symptoms and signs consistent with hydralazine-induced vasculitis to highlight that ophthalmological manifestations can be the first symptoms in patients with life-threatening dermatological conditions.
UNASSIGNED: To our knowledge, this report is the first case of hydralazine-induced vasculitis initially presenting with ocular manifestations.
摘要:
未经证实:本研究的目的是报告一例肼屈嗪诱发的血管炎患者的眼部表现。
未经证实:一名88岁女性因下消化道出血入院。入院9天后,她出现了双侧结膜化疗和注射,迅速发展为眶周皮肤的成组起泡性爆发,脸,和脖子。经过广泛的测试和评估,她的研究结果被诊断为肼屈嗪诱导的血管炎。静脉内类固醇治疗和停药肼屈嗪可改善皮肤和眼部表现。在此,我们描述了成年患者的临床过程,其症状和体征与肼屈嗪诱发的血管炎一致,以强调眼科表现可能是危及生命的皮肤病患者的首发症状。
未经授权:据我们所知,本报告是首例最初表现为眼部表现的肼屈嗪诱导的血管炎。
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