PDF(Pubmed)
Abstract：
This study includes diagnostic efficacy of the antemortem, combined use of ultrasonography and magnetic resonance imaging (MRI) for the diagnosis of anterior segment dysgenesis. A 7-day-old male Holstein calf presented with progressive unilateral exophthalmos associated with enlargement of the right eyeball soon after birth. Ultrasonography of the enlarged right eyeball showed (1) a 2-cm-thick echogenic parenchymal lesion filling the anterior region of the right eyeball, (2) excess accumulation of the anechoic vitreous humor, and (3) absence of the lens structure. Antemortem examination using T2-weighted and fluid-attenuated inversion recovery MRI revealed a thickened, hyperintense anterior lesion and absence of the lens structure. These imaging findings were suggestive of anterior segment dysgenesis. Antemortem imaging showed no abnormalities other than the abnormal structure and size of the right eyeball; therefore, enucleation of the right eye was performed, which allowed intact healing without suppuration. Ocular ultrasonography enhanced the diagnostic accuracy due to the characteristic ultrasonographic findings of a thickened anterior lesion and absence of the lens structure in the eyeball, suggestive of anterior segment dysgenesis.
摘要：
这项研究包括死亡前的诊断功效，联合使用超声和磁共振成像（MRI）诊断眼前节发育不全。7天大的雄性荷斯坦小牛出生后不久出现进行性单侧眼球突出，并伴有右眼球增大。扩大的右眼球的超声检查显示（1）一个2厘米厚的回声实质病变填充右眼球的前部区域，(2)消声玻璃体的过度积累，和(3)不存在透镜结构。使用T2加权和流体衰减反转恢复MRI进行的尸检显示增厚，高强度前部病变和晶状体结构缺失。这些影像学发现提示前节发育不全。除了右眼球的异常结构和大小外，前颅影像学没有其他异常；因此，进行右眼摘除,允许完整的愈合而不化脓。由于前病变增厚和眼球内晶状体结构缺失的特征性超声表现，眼部超声检查提高了诊断准确性。提示前节发育不全。
