PDF(Pubmed)
Abstract：
Nevus comedonicus (NC) is a rare developmental anomaly of the folliculosebaceous apparatus, which appears as numerous dilated papules containing firm, darkly pigmented, horny plugs. It appears shortly after birth and mostly before the age of 10; however, late-onset cases have been reported. There is no gender or racial predilection. Moreover, NC can be a component of nevus comedonicus syndrome, a neurocutaneous disorder with skeletal, ocular, and central nervous system abnormalities. EHK properties in NC are not a common finding and are rarely seen in association with each other. This paper reports a healthy, 27-year-old young woman who has been developing numbers of asymptomatic unilateral linear skin lesions on her chest, waist, right thigh, and popliteal fossa in a unilateral linear pattern over ten years. Skin biopsy revealed dilated follicular ostia with orthokeratotic hyperkeratosis, columns of parakeratosis, cornoid flagellation, epidermolytic hyperkeratosis, and mild acanthosis on its wall.
摘要：
粉刺痣（NC）是毛囊皮脂腺器官的罕见发育异常，看起来像许多扩张的丘疹，含有坚硬的，深色色素，角质插头。它出现在出生后不久，大多在10岁之前；然而，已经报道了迟发性病例。没有性别或种族偏好。此外，NC可能是粉刺痣综合征的一个组成部分，骨骼神经皮肤疾病，眼,中枢神经系统异常.NC中的EHK属性并不常见，并且很少与彼此相关联。这篇论文报道了一个健康的，一名27岁的年轻女性，她的胸部出现了许多无症状的单侧线性皮肤病变，腰部,右大腿,和pop窝呈单侧线性模式超过十年。皮肤活检显示滤泡口扩张伴角膜角化过度，角化不全的列，触角鞭打,表皮松解性角化过度，墙上有轻度棘皮病.
