Abstract：
A diastereoselective synthesis of the β-anomer of glycinamide ribonucleotide (β-GAR) has been developed. The synthesis was accomplished in nine steps from D-ribose and occurred in 5% overall yield. The route provided material on the multi-milligram scale. The synthetic β-GAR formed was remarkably resistant to anomerization both in solution and as a solid.
摘要：
已开发出甘氨酰胺核糖核苷酸（β-GAR）的β-端基异构体的非对映选择性合成。从D-核糖在9个步骤中完成合成,并且以5%的总产率进行合成。该路线提供了几毫克规模的材料。所形成的合成β-GAR在溶液中和作为固体对阴离子化具有显著的抗性。
