Inflammatory myofibroblastic tumor in the retromolar region of an 8-year-old child: A rare finding.

一个 8 岁儿童磨牙后区域的炎性肌纤维母细胞瘤 ： 一个罕见的发现。

• 发表时间: Feb 2022
• 来源期刊: J Oral Maxillofac Pathol
• DOI: 10.4103/jomfp.jomfp_363_20
• PMID: 35450238
• 文章类型: Case Reports
• 作者列表: Patil PH,Pereira T,Winnier JJ,Shetty JS,Patil PH,Pereira T,Winnier JJ,Shetty JS

关键词: Immunohistochemistry; inflammatory myofibroblastic tumor; retromolar; Immunohistochemistry; inflammatory myofibroblastic tumor; retromolar

Abstract

Inflammatory myofibroblastic tumor (IMT) of the oral cavity is an extremely rare finding. The etiology and pathogenesis of IMT is controversial and unclear. The tumor requires complete surgical excision and continuous monitoring of clinical consequences. The present article describes the clinical, histological, operative and immunohistochemical features of a case of IMT in the mandibular retromolar region of an 8-year-old male. Histologically, the lesion shows myofibroblastic spindle cell proliferations with infiltrative margins in an inflammatory background. Immunohistochemically, the myofibroblastic spindle cells in the present case were positive for α-smooth muscle actin and CD68 due to which the diagnosis of IMT was confirmed.

摘要

口腔炎症性肌纤维母细胞瘤（IMT）是极为罕见的发现。IMT的病因及发病机制存在争议,目前尚不清楚。肿瘤需要完整的手术切除和持续监测临床后果。本文描述了临床，组织学,一名8岁男性下颌磨牙后区域IMT的手术和免疫组织化学特征。组织学上,病变显示肌纤维母细胞梭形细胞增殖，并在炎症背景下浸润边缘。免疫组织化学，在本例中，肌纤维母细胞梭形细胞对α-平滑肌肌动蛋白和CD68呈阳性，因此证实了IMT的诊断。