Abstract：
BACKGROUND: Hydrophilic coated catheters are recommended to reduce the side effects of intermittent catheterization (IC) in patients with bladder dysfunction. However, there is lack of Level one evidence to support the use of this intervention.
METHODS: Several electronic databases were systematically searched to evaluate complication incidences for hydrophilic coated (HC) and non-hydrophilic catheters (NHC).
RESULTS: Twelve studies were eligible for inclusion in the review. The meta-analyses exploring microscopic hematuria frequencies (RR = 0.69; 95% CI 0.52-0.90) and urethral stricture frequencies (RR = 0.28; 95% CI 0.13-0.60) showed a lower risk ratio associated with HC in comparison to NHC, whereas gross hematuria was no statistically significant difference in two groups. Subgroup analyses of gross hematuria which was grouped according to \"catheterization frequency\", \"single/multiple catheterization\" and \"self/other catheterization\" were performed and the values of combined RR were also no statistically significant difference.
CONCLUSIONS: Compared with non-hydrophilic catheters, the hydrophilic coated catheters have positive significance in reducing the incidence of urethral microtrauma and the urethral stricture. However, more studies are warranted for evaluating effects of hydrophilic coated catheters on the incidence of gross hematuria.
METHODS: Several electronic databases were systematically searched to evaluate complication incidences for hydrophilic coated (HC) and non-hydrophilic catheters (NHC).
RESULTS: Twelve studies were eligible for inclusion in the review. The meta-analyses exploring microscopic hematuria frequencies (RR = 0.69; 95% CI 0.52-0.90) and urethral stricture frequencies (RR = 0.28; 95% CI 0.13-0.60) showed a lower risk ratio associated with HC in comparison to NHC, whereas gross hematuria was no statistically significant difference in two groups. Subgroup analyses of gross hematuria which was grouped according to \"catheterization frequency\", \"single/multiple catheterization\" and \"self/other catheterization\" were performed and the values of combined RR were also no statistically significant difference.
CONCLUSIONS: Compared with non-hydrophilic catheters, the hydrophilic coated catheters have positive significance in reducing the incidence of urethral microtrauma and the urethral stricture. However, more studies are warranted for evaluating effects of hydrophilic coated catheters on the incidence of gross hematuria.
摘要：
背景：建议使用亲水涂层导管来减少膀胱功能障碍患者间歇性导尿（IC）的副作用。然而,缺乏支持使用这种干预措施的一级证据。
方法：系统搜索了几个电子数据库，以评估亲水性涂层（HC）和非亲水性导管（NHC）的并发症发生率。
结果：12项研究符合纳入评价的条件。研究显微镜下血尿频率（RR=0.69;95％CI0.52-0.90）和尿道狭窄频率（RR=0.28;95％CI0.13-0.60）的荟萃分析显示，与NHC相比，与HC相关的风险比更低。而肉眼血尿两组比较差异无统计学意义。根据“导尿频率”分组的肉眼血尿亚组分析，进行了“单/多导管插入”和“自我/其他导管插入”，合并RR值也无统计学差异。
结论：与非亲水性导管相比，亲水涂层导尿管对减少尿道外伤和尿道狭窄的发生具有积极的意义。然而,需要更多的研究来评估亲水性涂层导管对肉眼血尿发生率的影响.
方法：系统搜索了几个电子数据库，以评估亲水性涂层（HC）和非亲水性导管（NHC）的并发症发生率。
结果：12项研究符合纳入评价的条件。研究显微镜下血尿频率（RR=0.69;95％CI0.52-0.90）和尿道狭窄频率（RR=0.28;95％CI0.13-0.60）的荟萃分析显示，与NHC相比，与HC相关的风险比更低。而肉眼血尿两组比较差异无统计学意义。根据“导尿频率”分组的肉眼血尿亚组分析，进行了“单/多导管插入”和“自我/其他导管插入”，合并RR值也无统计学差异。
结论：与非亲水性导管相比，亲水涂层导尿管对减少尿道外伤和尿道狭窄的发生具有积极的意义。然而,需要更多的研究来评估亲水性涂层导管对肉眼血尿发生率的影响.
