PDF(Pubmed)
Abstract：
While chronic schistosomiasis is pathologically well defined, the acute form of the disease is less well understood. It is generally agreed that early lesions, such as lung nodules and bladder polyps, are reversible, which impedes identification of the time elapsed since exposure. The intermediate stage between the acute and the chronic forms of schistosomiasis requires further investigation, as does the clinical stage due to lesions remaining after treatment. With current schistosomiasis control efforts gradually progressing to elimination, there is a need to focus on post-transmission schistosomiasis, which not only refers to remaining lesions from previous infections, but also accounts for the potential presence of surviving worms after treatment. This issue is particularly salient for migrants from endemic to non-endemic countries and should be kept in mind for returning expatriates from schistosomiasis-endemic countries. Negative stool examination or urine filtration are generally taken as indicative of cure since rectoscopy for Schistosoma mansoni infection, or cystoscopy for S. haematobium infection, are rarely performed. However, pathology of affected organs may persist indefinitely, while potentially remaining live worms could produce additional pathology. Hence, post-transmission schistosomiasis can prevail for years after elimination of the disease, and thus, warrant further attention.
摘要：
虽然慢性血吸虫病在病理上是明确的，这种疾病的急性形式不太清楚。人们普遍认为早期病变，如肺结节和膀胱息肉，是可逆的，这阻碍了对曝光后经过的时间的识别。血吸虫病的急性和慢性形式之间的中间阶段需要进一步研究，由于治疗后仍有病变，临床阶段也是如此。随着当前血吸虫病防治工作逐步向消除方向推进,有必要关注传播后的血吸虫病，这不仅是指以前感染的残留病变，但也解释了治疗后存活的蠕虫的潜在存在。这个问题对于从流行国家到非流行国家的移民尤其突出，从血吸虫病流行国家返回的外籍人士应牢记。自从曼氏血吸虫感染行直肠镜检查以来，粪便检查阴性或尿液过滤通常被视为治愈的指示。或膀胱镜检查，很少执行。然而,受影响器官的病理可能会无限期持续，而潜在的活蠕虫可能会产生额外的病理。因此，传播后的血吸虫病可以在疾病消除后的数年内流行，因此，值得进一步关注。
