关键词: alcohol biomarkers biomimetic biosensor road accidents target analyte

Mesh : Biomarkers / analysis Biosensing Techniques Electrochemical Techniques Ethanol / analysis Humans Monitoring, Physiologic Sweat / chemistry

来  源:   DOI:10.3390/bios12040252

Abstract:
The continued focus on improving the quality of human life has encouraged the development of increasingly efficient, durable, and cost-effective products in healthcare. Over the last decade, there has been substantial development in the field of technical and interactive textiles that combine expertise in electronics, biology, chemistry, and physics. Most recently, the creation of textile biosensors capable of quantifying biometric data in biological fluids is being studied, to detect a specific disease or the physical condition of an individual. The ultimate goal is to provide access to medical diagnosis anytime and anywhere. Presently, alcohol is considered the most commonly used addictive substance worldwide, being one of the main causes of death in road accidents. Thus, it is important to think of solutions capable of minimizing this public health problem. Alcohol biosensors constitute an excellent tool to aid at improving road safety. Hence, this review explores concepts about alcohol biomarkers, the composition of human sweat and the correlation between alcohol and blood. Different components and requirements of a biosensor are reviewed, along with the electrochemical techniques to evaluate its performance, in addition to construction techniques of textile-based biosensors. Special attention is given to the determination of biomarkers that must be low cost and fast, so the use of biomimetic materials to recognize and detect the target analyte is turning into an attractive option to improve electrochemical behavior.
摘要:
对提高人类生活质量的持续关注鼓励了越来越高效的发展,耐用,和医疗保健中具有成本效益的产品。在过去的十年里,结合了电子专业知识的技术和交互式纺织品领域已经有了实质性的发展,生物学化学,和物理学。最近,正在研究能够量化生物流体中生物数据的纺织生物传感器的创建,检测特定疾病或个体的身体状况。最终目标是随时随地提供医疗诊断。目前,酒精被认为是世界上最常用的成瘾物质,是道路交通事故死亡的主要原因之一。因此,重要的是要考虑能够最大限度地减少这一公共卫生问题的解决方案。酒精生物传感器是改善道路安全的绝佳工具。因此,这篇综述探讨了有关酒精生物标志物的概念,人体汗液的成分以及酒精与血液的相关性。回顾了生物传感器的不同组件和要求,随着电化学技术来评估其性能,除了纺织生物传感器的构建技术。特别注意必须低成本和快速的生物标志物的确定,因此,使用仿生材料来识别和检测目标分析物正成为改善电化学行为的有吸引力的选择。
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