PDF(Pubmed)
Abstract：
Genome-wide genotype data from 48 carefully selected population samples of Transylvania-living Szeklers and non-Szekler Hungarians were analyzed by comparative analysis. Our analyses involved contemporary Hungarians living in Hungary, other Europeans, and Eurasian samples counting 530 individuals altogether. The source of the Szekler samples was the commune of Korond, Transylvania. The analyzed non-Szekler Hungarian samples were collected from villages with a history dating back to the era of the Árpád Dynasty. Population structure by principal component analysis and ancestry analysis also revealed a great within-group similarity of the analyzed Szeklers and non-Szekler Transylvanian Hungarians. These groups also showed similar genetic patterns with each other. Haplotype analyses using identity-by-descent segment discovering tools showed that average pairwise identity-by-descent sharing is similar in the investigated populations, but the Korond Szekler samples had higher average sharing with the Hungarians from Hungary than non-Szekler Transylvanian Hungarians. Average sharing results showed that both groups are isolated compared to other Europeans, and pointed out that the non-Szekler Transylvanian Hungarian inhabitants of the investigated Árpád Age villages are more isolated than investigated Szeklers from Korond. This was confirmed by our autozygosity analysis as well. Identity-by-descent segment analyses and 4-population tests also confirmed that these Hungarian-speaking Transylvanian ethnic groups are strongly related to Hungarians living in Hungary.
摘要：
通过比较分析，分析了来自48个精心选择的Transylvania居住的Szekler和非Szekler匈牙利人的人群样本的全基因组基因型数据。我们的分析涉及生活在匈牙利的当代匈牙利人，其他欧洲人,和欧亚样本共计数530个人。塞克勒样本的来源是科隆镇,Transylvania.分析的非Szekler匈牙利样本是从村庄收集的，其历史可以追溯到阿帕德王朝时代。通过主成分分析和祖先分析得出的人口结构也揭示了所分析的Szeklers和非SzeklerTransylvania匈牙利人的群体内部相似性。这些群体也显示出彼此相似的遗传模式。使用按血统分类的身份发现工具进行的单倍型分析显示，在所调查的人群中，按血统分类的平均成对身份共享是相似的。但是科隆·塞克勒样本与匈牙利的匈牙利人的平均分享率高于非塞克勒·Transylvania匈牙利人。平均分享结果显示，与其他欧洲人相比，这两个群体都是孤立的，并指出，被调查的阿帕德时代村庄的非塞克勒·Transylvania匈牙利居民比被调查的科隆的塞克勒更为孤立。这也通过我们的自合性分析得到证实。按血统分类的身份分析和4人口测试也证实，这些讲匈牙利语的Transylvanvanian族与居住在匈牙利的匈牙利人密切相关。
