Abstract：
The aim of this study is to verify the role of laminar necrosis (LN) in the diagnosis of hypoxic damage of the placenta. This is a retrospective case-control study in which 50 cases with laminar necrosis were compared with 100 gestational age-matched controls without laminar necrosis in a 1:2 ratio. The parameters analyzed were: the presence of other placental lesions, obstetric characteristics and neonatal outcome. For each of the 50 cases, the area affected by the lesion was detected, and the lesions were classified into three groups based on the morphology and time of onset of the lesion in order to understand whether these characteristics of the lesion had a clinical-pathology. The results showed that including the search for LN among placental lesions generally examined is useful to guide the pathologist in the diagnosis of placental dysfunction of hypoxic origin.
摘要：
本研究的目的是验证层状坏死（LN）在胎盘缺氧损伤诊断中的作用。这是一项回顾性病例对照研究，其中以1：2的比例将50例层状坏死患者与100例胎龄匹配的无层状坏死的对照进行了比较。分析的参数是：其他胎盘病变的存在，产科特征和新生儿结局。对于50个案例中的每一个，检测到受病变影响的区域，根据病变的形态和发病时间将病变分为三组，以了解病变的这些特征是否具有临床病理学特征。结果表明，在通常检查的胎盘病变中搜索LN有助于指导病理学家诊断缺氧起源的胎盘功能障碍。
