PDF(Pubmed)
Abstract：
Esophageal cancer is the ninth most common cancer all over the world and is sixth in the list of cancer-related mortality. Here in this report, we present an elderly male with solitary subcutaneous metastasis to right thigh 2 years following esophagectomy for esophageal adenocarcinoma. Operative notes revealed inadequate margins on frozen section analysis during initial resection, which were subsequently revised. Postoperative histopathology showed ypT3N0M0 Grade 3 mucin-secreting adenocarcinoma. A wedge biopsy from the thigh growth revealed metastatic mucinous adenocarcinoma. Positron Emission Tomography (PET) was done, which showed a higher tracer uptake in the ulcero-proliferative lesion arising from the subcutaneous plane in the right thigh with no evidence of any other metastasis or recurrence at the primary site. As the reported incidence of distant unexpected metastases is growing, careful physical examination with a preoperative PET-CT is indispensable. Further knowledge on options on treatment of such isolated cutaneous metastasis needs to be studied by the scientific community.
摘要：
食管癌是世界上第九大最常见的癌症，在癌症相关死亡率列表中排名第六。在这份报告中，我们介绍了一名老年男性，在食管腺癌切除2年后，右大腿有孤立皮下转移。手术记录显示初始切除期间冷冻切片分析的切缘不足，随后进行了修订。术后病理示：ypT3N0M03级粘蛋白分泌腺癌。大腿生长的楔形活检显示转移性粘液腺癌。正电子发射断层扫描（PET）完成，在右大腿皮下平面引起的溃疡增生性病变中显示出较高的示踪剂摄取，在原发部位没有任何其他转移或复发的证据。据报道，远处意外转移的发生率正在增加，术前使用PET-CT进行仔细的体格检查是必不可少的。科学界需要研究有关治疗这种孤立的皮肤转移的选择的进一步知识。
