关键词: Actin Calcium Muscle contraction Myosin Relaxing factor Troponin

Mesh : Biophysics Calcium / metabolism Calcium Signaling / physiology Ions Molecular Biology Muscle Contraction / physiology

来  源:   DOI:10.1016/j.pbiomolbio.2022.03.009

Abstract:
The 1968 review article on Calcium ion and muscle contraction by Setsuro Ebashi and Makoto Endo is one of the highest cited in the journal since it was required reading in the early days of understanding what triggers contraction of the myofilaments. It correctly identified the major steps in excitation-contraction coupling and still inspires mathematical models of muscle activity today. It also successfully identified the role of troponin.
摘要:
SetsuroEbashi和MakotoEndo在1968年发表的关于钙离子和肌肉收缩的评论文章是该杂志上引用最多的文章之一,因为在了解触发肌丝收缩的早期就需要阅读。它正确地确定了兴奋-收缩耦合的主要步骤,并且仍然启发了今天的肌肉活动的数学模型。它还成功地鉴定了肌钙蛋白的作用。
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