PDF(Pubmed)
Abstract：
UNASSIGNED: At present, the surgical treatment of occult tethered cord syndrome (OTCS) in children is mostly two types of minimally invasive surgery: filum terminalis laxity or filum terminalectomy. The clinical efficacy and safety of minimally invasive treatment and conservative treatment are still unclear. Therefore, this study will use the advantages of systematic review and meta-analysis to evaluate the objectivity, and explore the effect of minimally invasive surgery on children with occult tethered cord syndrome.
UNASSIGNED: A computer search was used to search PubMed, Embase, CNKI, Wanfang Database and other literature search websites about the randomized controlled trials (RCTs) of minimally invasive surgery in children with occult tethered cord syndrome and spinal lipoma. Professional journals were manually searched to avoid omissions. The search keywords were: occult myelolipoma, occult tethered cord syndrome, surgical treatment of tethered cord syndrome, occult tethered cord syndrome.
UNASSIGNED: A total of 6 relevant literatures that could be used for meta-analysis were selected. A total of 425 subjects were included in the article, of which 132 were treated conservatively and 293 were treated surgically. The heterogeneity detection test statistics of the included studies were Chi2 (Chi-squared test) =8.18, df (degree of freedom) =5, I2=39%<50%, Z=2.53, and the homogeneity of the included studies was good. The number of unimproved cases under conservative treatment was 40, accounting for 30.30%; the number of unimproved cases under surgical treatment was 33, accounting for 11.26%, and the total unimproved rate of the two groups accounted for 17.17%. The unimproved rate of the experimental group was significantly lower than that of the control group, and the difference was statistically significant (P=0.01). The results of bias analysis showed that there was no significant bias in the literature included in this study.
UNASSIGNED: Meta-analysis results confirmed that minimally invasive surgery has a significant effect on the treatment of occult children with tethered cord syndrome. However, due to the small sample size of the included literature, further evaluation of the treatment risk is required.
UNASSIGNED: A computer search was used to search PubMed, Embase, CNKI, Wanfang Database and other literature search websites about the randomized controlled trials (RCTs) of minimally invasive surgery in children with occult tethered cord syndrome and spinal lipoma. Professional journals were manually searched to avoid omissions. The search keywords were: occult myelolipoma, occult tethered cord syndrome, surgical treatment of tethered cord syndrome, occult tethered cord syndrome.
UNASSIGNED: A total of 6 relevant literatures that could be used for meta-analysis were selected. A total of 425 subjects were included in the article, of which 132 were treated conservatively and 293 were treated surgically. The heterogeneity detection test statistics of the included studies were Chi2 (Chi-squared test) =8.18, df (degree of freedom) =5, I2=39%<50%, Z=2.53, and the homogeneity of the included studies was good. The number of unimproved cases under conservative treatment was 40, accounting for 30.30%; the number of unimproved cases under surgical treatment was 33, accounting for 11.26%, and the total unimproved rate of the two groups accounted for 17.17%. The unimproved rate of the experimental group was significantly lower than that of the control group, and the difference was statistically significant (P=0.01). The results of bias analysis showed that there was no significant bias in the literature included in this study.
UNASSIGNED: Meta-analysis results confirmed that minimally invasive surgery has a significant effect on the treatment of occult children with tethered cord syndrome. However, due to the small sample size of the included literature, further evaluation of the treatment risk is required.
摘要：
未经批准：目前，儿童隐匿性脊髓栓系综合征（OTCS）的手术治疗主要是两种类型的微创手术：纤维终末松弛或纤维终末切除术。微创治疗和保守治疗的临床疗效和安全性尚不清楚。因此,本研究将利用系统综述和荟萃分析的优势来评价客观性，探讨微创手术治疗小儿隐匿性脊髓栓系综合征的效果。
未经评估：使用计算机搜索来搜索PubMed，Embase,CNKI,万方数据库和其他文献检索网站关于儿童隐匿性脊髓栓系综合征和脊髓脂肪瘤微创手术的随机对照试验(RCT)。手动搜索专业期刊以避免遗漏。搜索关键词是:隐匿性骨髓脂肪瘤,隐匿性脊髓栓系综合征,脊髓栓系综合征的外科治疗,隐匿性脊髓栓系综合征。
UNASSIGNED：共选取6篇可用于Meta分析的相关文献。本文共纳入425名受试者,其中132例保守治疗，293例手术治疗。纳入研究的异质性检测检验统计量为Chi2(卡方检验)=8.18,df(自由度)=5,I2=39%<50%,Z=2.53，纳入研究的同质性好。保守治疗未好转病例数40例,占30.30%;手术治疗未好转病例数33例,占11.26%,两组总的未好转率占17.17%。实验组的未好转率明显低于对照组,差异有统计学意义(P=0.01)。偏倚分析结果显示,纳入本研究的文献中不存在显著偏倚。
UNASSIGNED：荟萃分析结果证实，微创手术对隐匿性脊髓栓系综合征患儿的治疗具有显着效果。然而,由于纳入文献的样本量小，需要进一步评估治疗风险.
未经评估：使用计算机搜索来搜索PubMed，Embase,CNKI,万方数据库和其他文献检索网站关于儿童隐匿性脊髓栓系综合征和脊髓脂肪瘤微创手术的随机对照试验(RCT)。手动搜索专业期刊以避免遗漏。搜索关键词是:隐匿性骨髓脂肪瘤,隐匿性脊髓栓系综合征,脊髓栓系综合征的外科治疗,隐匿性脊髓栓系综合征。
UNASSIGNED：共选取6篇可用于Meta分析的相关文献。本文共纳入425名受试者,其中132例保守治疗，293例手术治疗。纳入研究的异质性检测检验统计量为Chi2(卡方检验)=8.18,df(自由度)=5,I2=39%<50%,Z=2.53，纳入研究的同质性好。保守治疗未好转病例数40例,占30.30%;手术治疗未好转病例数33例,占11.26%,两组总的未好转率占17.17%。实验组的未好转率明显低于对照组,差异有统计学意义(P=0.01)。偏倚分析结果显示,纳入本研究的文献中不存在显著偏倚。
UNASSIGNED：荟萃分析结果证实，微创手术对隐匿性脊髓栓系综合征患儿的治疗具有显着效果。然而,由于纳入文献的样本量小，需要进一步评估治疗风险.
