在哺乳动物细胞中表达编码 O6 - 烷基鸟嘌呤烷基转移酶的截短的大肠杆菌基因降低了烷化剂的毒性作用。
Mesh : Alkylating Agents / toxicity Alkylation Cells, Cultured Escherichia coli / genetics Guanine / metabolism Methyltransferases / genetics O(6)-Methylguanine-DNA Methyltransferase Plasmids Repetitive Sequences, Nucleic Acid Transfection
来 源:
DOI:10.1093/carcin/7.12.2081
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