UNASSIGNED: We searched the following English electronic databases: PubMed, Embase, Cochrane Central Register of Controlled Trials, and Google Scholar Engine. Published studies involving neutropenic diets (study group) and control diets (control group) in oncology patients with neutropenia were searched. The focus of the meta-analysis was on the outcomes of infection and mortality rates. A subgroup analysis was also performed.
UNASSIGNED: A total of 6 studies were included, with a total sample size of 1114 patients. The patients in the study group had a similar infection rate compared with the patients in the control group (P = 0.11). The patients in the study group had a similar mortality rate compared with the patients in the control group (P = 0.74). Another subgroup analysis showed that the incidence of infection was also similar for pediatric (P = 0.74) and adult (P = 0.11) oncology patients between the study and control groups.
UNASSIGNED: Based on the current evidence, this meta-analysis showed that the application of a neutropenic diet cannot reduce the risk of infection and mortality in oncology patients with neutropenia. However, more rigorous randomized controlled trials are needed to confirm this conclusion in the future.
UNASSIGNED:我们搜索了以下英文电子数据库:PubMed,Embase,Cochrane中央控制试验登记册,谷歌学者引擎。搜索了涉及中性粒细胞减少症肿瘤患者中性粒细胞减少症饮食(研究组)和对照饮食(对照组)的已发表研究。荟萃分析的重点是感染和死亡率的结果。还进行了亚组分析。
未经评估:共纳入6项研究,总样本量为1114名患者。研究组患者的感染率与对照组相似(P=0.11)。研究组患者的死亡率与对照组患者相似(P=0.74)。另一个亚组分析显示,研究组和对照组之间的儿科(P=0.74)和成人(P=0.11)肿瘤患者的感染发生率也相似。
未经批准:根据目前的证据,这项荟萃分析显示,中性粒细胞减少性饮食的应用不能降低肿瘤中性粒细胞减少症患者的感染风险和死亡率.然而,未来需要更严格的随机对照试验来证实这一结论.